Bulletin of the Korean Chemical Society

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An Efficient and Concise Synthesis of Biologically Interesting Natural Flemichapparin A, Flemingin A, Flemingin D, and Their Non-natural Analogues

  • Lee, Yong-Rok (School of Chemical Engineering and Technology, Yeungnam University) ;
  • Xia, Likai (School of Chemical Engineering and Technology, Yeungnam University)
  • Published : 2007.09.20
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Abstract

The efficient and concise synthesis of natural and non-natural pyranochalcones was achieved from readily available 2,4,5-trihydroxyacetophenone. The key steps in the synthetic strategy were ethylenediamine diacetate-catalyzed benzopyran formation and aldol reactions.

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