Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Concise Synthesis of Biologically Interesting Mollugin and Its Analogues

  • Lee, Yong-Rok (School of Chemical Engineering and Technology, Yeungnam University) ;
  • Wang, Xue (School of Chemical Engineering and Technology, Yeungnam University) ;
  • Kim, Yun-Mi (School of Chemical Engineering and Technology, Yeungnam University) ;
  • Shim, Jae-Jin (School of Chemical Engineering and Technology, Yeungnam University) ;
  • Kim, Byung-Nam (School of Chemical Engineering and Technology, Yeungnam University) ;
  • Han, Do-Hung (School of Chemical Engineering and Technology, Yeungnam University)
  • Published : 2007.10.20
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Abstract

The synthesis of naturally occurring mollugin and its analogues, 3,4-dihydromollugin, cis-3,4-dihydroxy-3,4- dihydromollugin, and trans-3,4-dihydroxy-3,4-dihydromollugin was achieved starting from 1,4-dihydroxynaphthalene- 2-carboxylic acid. The key reaction is an electrocyclization for pyranyl ring formation in the presence of PhB(OH)2/AcOH.

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References

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