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Effect of Saengshik on Blood Glucose Response in Healthy Subjects

생식조성이 정상성인의 혈당반응에 미치는 영향

  • 김화영 ((주)이롬 생명과학연구원) ;
  • 홍성길 ((주)이롬 생명과학연구원) ;
  • 황성주 ((주)이롬 생명과학연구원) ;
  • 목철균 (경원대학교 식품생물공학과) ;
  • 박미현 ((주)이롬 생명과학연구원) ;
  • 이주연 ((주)이롬 생명과학연구원)
  • Published : 2007.12.31

Abstract

The purposes of this study were to investigate the effect of Saengshik on blood glucose level of normal subject and to explore the marketing possibility of four kinds of Saengshik (ES, HS, BS, SS) as alternative diabetic meals. Blood glucose levels of healthy volunteers was measured at 15, 30, 45, 60, 75, 90, 105 and 120 minutes after taking Saengshik and 50 g glucose. Blood glucose response areas, glycemic index (GI) and glycemic load (GL) were calculated from the glucose response. The Saengshik showed a significantly lower glucose level than the glucose. The glycemic index (GI) of ES showed $43.1{\pm}12.6$, which belonged to low GI foods (GI of 55 or less). Other samples (HS, BS, SS) could be classified as intermediate GI foods ranging $56{\sim}69$ of GI. Saengshik showed a gentle rising and falling pattern showing moderate left area ratio and right area ratio on blood glucose curve. The GL of ES showed 14.1 while HS, BS and SS did $19.2{\sim}19.5$. The results indicated that Saengshik may have a beneficial effect on a diabetic.

본 연구는 생식을 정상성인에게 섭취시켰을 때 혈당반응에 미치는 영향을 연구하고, 생식의 혈당지수를 구하여 당뇨병 환자의 혈당 조절식으로 이용가능성을 조사하기 위하여 시판중인 생식 4(ES, HS, BS, SS)종을 섭취 전, 섭취 후 120분 동안 15분 간격으로 채혈하여 혈당을 측정하였다. 생식 섭취 후 혈당수치는 포도당 섭취시보다 전반적으로 낮게 나타났으며, ES는 $15{\sim}75$분, SS는 $15{\sim}75$분, HS는 $15{\sim}45$분, BS는 15분 후의 혈당이 포도당보다 유의적으로 낮게 나타났다. 식이 섭취 후 측정한 시간에 따른 혈당값을 이용하여 혈당반응 곡선의 면적을 구한 결과, 생식 섭취군은 포도당 섭취군보다 면적이 적은 것으로 나타났으며, 상기 면적을 이용하여 GI를 산출한 결과, ES는 $43.1{\pm}12.6$으로 Low GI(55이하) 범위에 속하였으며, 그 외 생식은 Medium GI($56{\sim}69$) 범위에 속하였다. 생식의 소화, 흡수 형태를 알아보기 위하여 상기에서 구한 혈당반응곡선 면적을 일반적인 최고 혈당값 나타내는 시간인 30분을 전후로 하여 LAR(혈당상승기)과 RAR(혈당감소기)을 구한 결과, 생식은 혈당 상승과 감소를 완만하게 해주는 것으로 나타났으며, 생식섭취 후 최고 혈당값을 포도당을 섭취했을 때보다 유의적으로 감소시켰으며, 최고 혈당값을 나타내는 시간은 생식 ES에서 연장되는 경향을 나타내었다. 위의 결과들을 종합해 볼 때, 생식의 섭취는 체내 당의 소화와 흡수 과정을 천천히 진행시키며, 식후 최고 혈당수치를 감소시켜 전반적인 혈당반응을 원만하게 하는 것으로 나타났으며, GL은 ES(14.1)이 가장 낮았으며 HS, BS, SS($19.2{\sim}19.5$) 수준으로 GL 역시 낮은 수치를 나타내었다. 위의 연구결과 생식은 당뇨병 환자의 식후 혈당상승을 조절하여 유익한 영향을 미칠 수 있을 것으로 사료되며, 생식의 조성에 따라 그 효과는 차이를 보이며, 사용하는 당의 특징과 곡류군의 조성, 식이섬유의 종류, 과일소재의 첨가 등에 따라 달라지므로 추후 심화된 연구가 필요할 것이다.

Keywords

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