대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제27권4호
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- Pages.811-821
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- 2006
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- 1226-9174(pISSN)
고혈당 흰쥐에서 상엽(桑葉)의 혈당 조절과 항산화 작용에 관한 연구
Effects of the Mori folium Extract in Streptozotocin-Induced Diabetic Rats
- Kim, Oh-Gon (Department of Internal Medicine, College of Korean Medicine, Dongguk University) ;
- Jeong, Ji-Cheon (Department of Internal Medicine, College of Korean Medicine, Dongguk University)
- 발행 : 2006.12.31
초록
Objectives : Diabetes is a disease in which the body does not produce or properly use insulin. Etiological studies of diabetes and its complications showed that oxidative stress might play a major role. Therefore, many methods have been tried to regulate oxygen free radicals for treating diabetes and its complications. Because Mori foliumhas been known to be effective for the treatment of diabetes, the methanol extract of Mori folium was tested for its effectiveness in reducing the oxidative stress induced by streptozotocin. Methods : The crushed Mori folium was extracted 3 times, each time with 3 volumes of methyl alcohol at