대한본초학회지 (The Korea Journal of Herbology)
- 제21권4호
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- Pages.189-195
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- 2006
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
뇌허혈로 인한 흰쥐에서의 기억력 및 학습효과 저해에 대한 황금의 보호효과
Protective effects of Scutellariae Radix on impairments in learning and memory induced by brain ischemia in rats
- 김영옥 (경희대학교 동서의학대학원) ;
- 이세나 (세명대학교 한의과대학) ;
- 김명규 (우석대학교 약학대학) ;
- 부영민 (우석대학교 약학대학) ;
- 김선여 (경희대학교 동서의학대학원) ;
- 김호철 (경희대학교 동서의학대학원) ;
- 임강현 (세명대학교 한의과대학)
- Kim, Young-Ock (Graduate School of East-West Medical Science, Kyung Hee University) ;
- Lee, Se-Na (College of Korean Medicine, Semyung University) ;
- Kim, Myung-Gyou (College of Pharmacy, Woosuk University) ;
- Boo, Yung-Min (College of Pharmacy, Woosuk University) ;
- Kim, Sun-Yeou (Graduate School of East-West Medical Science, Kyung Hee University) ;
- Kim, Ho-Cheol (Graduate School of East-West Medical Science, Kyung Hee University) ;
- Leem, Kang-Hyun (College of Korean Medicine, Semyung University)
- 발행 : 2006.12.30
초록
Objectives : It has been reported previously that the roots of Scutellaria baicalensis (known as Huang-Gum in Korean, henceforth referred to as S. baicalensis) could prevent neuronal cell death after global cerebral ischemia. In Genuine Korean medicine, S. baicalensis is known to relieve fever in upper body, and it was thus thought to be able to alleviate deteriorations in brain function. Methods : The protective effects of S. baicalensis against post-stroke memory retardation using 4-vessel occlusion model were examined in the present study. Results : S. baicalensis was shown to significantly alleviate the deficits in learning and memory by increasing the fraction of time spent in the quadrant in which the platform was initially placed (
키워드