대한본초학회지 (The Korea Journal of Herbology)
- 제21권3호
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- Pages.47-54
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- 2006
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
인진호탕(茵蔯蒿湯)과 한인진호탕(韓茵蔯蒿湯)이 알코올 투여(投與)로 유발(誘發)된 흰쥐의 고지혈증(高脂血症)과 간(肝) 손상(損傷)의 예방(豫防)에 미치는 영향(影響)
Preventive effects of Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol
- 김유창 (대구한의대학교 한의과대학) ;
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김승모
(대구한의대학교 한의과대학) ;
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박지하
(대구한의대학교 한의과대학) ;
- 서부일 (대구한의대학교 한의과대학) ;
-
최홍식
(대구한의대학교 한의과대학)
- Kim, You-Chang (Dept of Oriental Medicine, Daegu Haany University) ;
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Kim, Seong-Mo
(Dept of Oriental Medicine, Daegu Haany University) ;
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Park, Ji-Ha
(Dept of Oriental Medicine, Daegu Haany University) ;
- Seo, Bu-Il (Dept of Oriental Medicine, Daegu Haany University) ;
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Choi, Hong-Sik
(Dept of Oriental Medicine, Daegu Haany University)
- 발행 : 2006.09.30
초록
Objectives : This study was performed to compare the preventive effect of water extracts from Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And each extract was administrated for the same period. We measured the serum component in rat's blood, body weight and weight of liver. Results : 1. At first, we observed effects of Injinho-tang and Haninjinho-tang on hyperlipidemia induced by alcohol. Injinho-tang group showed significant decrease of triglyceride, body weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of total cholesterol, triglyceride in comparison with those of the control group. I 2. At second, we observed effects of Injinho-tang and Haninjinho-tang on liver damage induced by alcohol. lnjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase), ALP (alkaline phosphatase), liver weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase) in comparison with those of the control group. Conclusion : Reviewing these experimental results, it appears that water extracts from Injinho-tang and Haninjinho-tang have pharmaceutical preventive efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.
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