Journal of Korean Traditional Oncology (대한암한의학회지)

Korean Association of Traditional Oncology (대한암한의학회)
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The Study on the Safety and Case Series of the Acute Lymphocytic Leukemia using Rhus Verniciflua Stokes Extract (Nexia)

건칠(乾漆) 추출물(Nexia)의 독성 실험과 급성 림프 구성 백혈병환자의 임상증례군 보고

  • Park, Jae-Woo (Department of Oriental Internal Medicine, College of Oriental Medicine, Kyung Hee University) ;
  • Kim, Kyung-Suk (MU Integrative Cancer Center, East-West Medical Center, Kyung Hee University) ;
  • Jung, Hyun-Sik (MU Integrative Cancer Center, East-West Medical Center, Kyung Hee University) ;
  • Choi, Won-Cheol (MU Integrative Cancer Center, East-West Medical Center, Kyung Hee University) ;
  • Yoon, Seong-Woo (Department of Oriental Internal Medicine, College of Oriental Medicine, Kyung Hee University, MU Integrative Cancer Center, East-West Medical Center, Kyung Hee University)
  • 박재우 (경희대학교 한의과대학 한방소화기내과) ;
  • 김경석 (경희대학교 동서신의학병원 통합암센터) ;
  • 정현식 (경희대학교 동서신의학병원 통합암센터) ;
  • 최원철 (경희대학교 동서신의학병원 통합암센터) ;
  • 윤성우 (경희대학교 한의과대학 한방소화기내과, 경희대학교 동서신의학병원 통합암센터)
  • Published : 2006.12.29
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Abstract

This study was undertaken to evaluate safety and antitumor activity of Nexia, a processed extract of Rhus verniciflua STOKES by heating according to Korean patent 0504160 through toxicology, cancer research and clinical application. Nexia did not exhibit any toxicological symptoms through 13 week continuous treatment, dosage accumulation study and anaphylaxis response. The lifespan of four patients with acute lymphocytic leukemia under complete remission were 110, 83, 97, and 86 months after treatment of Nexia, respectively. These data suggest that Nexia, a processed extract by removing allergen from Rhus verniciflua STOKES, may have safety and antitumor activity and also still need continuous study on its mechanism and clinical trial.

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