Journal of Dairy Science and Biotechnology
- Volume 24 Issue 2
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- Pages.21-24
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- 2006
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- 2733-4554(pISSN)
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- 2733-4562(eISSN)
Health Promoting Effects of Lactoferrin from Milk
- Shimizu, Hirohiko (NRL Pharma Inc.) ;
- Ando, Kunio (NRL Pharma Inc.) ;
- Hoshino, Tatsuo (NRL Pharma Inc.)
- Published : 2006.11.22
Abstract
The ubiquitous presence of lactoferrin(LF) receptor in human as reported by the research group of Prof. Bo Lonnerdal, Univ. California (Suzuki, Y. A.,2001) encouraged us to search for the unknown physiological roles of Lf. Under the collaboration with Prof. Etsumori Harada, Tottori Univ., and his research group, we have found two novel biological activities of LF as the control of the lipid metabolism and the effect on the central nervous system. Relating to the lipid metabolism, LF could, in animal experiments, reduce triglyceride and total cholesterol both in blood and liver (Takeuchi, T et αl., 2003). LF increased plasms HDL-C and lowered LDL-C. In the central nervous system, LF showed anti-nociceptive activity mediated by
Keywords
- lactoferrin(LF) receptor;
- central nervous system;
- anti-nociceptive activity;
- analgesic action;
- opioid mediated suppressive effect