Journal of Biomedical Engineering Research (대한의용생체공학회:의공학회지)

The Korean Society of Medical and Biological Engineering (대한의용생체공학회)
권호 표지
DOI QR코드

DOI QR Code

An Extensive Analysis of High-density Electroencephalogram during Semantic Decision of Visually Presented Words

  • Kim, Kyung-Hwan (Department of Biomedical Engineering, College of Health Science, Yonsei University) ;
  • Kim, Ja-Hyun (Department of Biomedical Engineering, College of Health Science, Yonsei University)
  • Published : 2006.08.01
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study was to investigate the spatiotemporal cortical activation pattern and functional connectivity during visual perception of words. 61 channel recordings of electroencephalogram were obtained from 15 subjects while they were judging the meaning of Korean, English, and Chinese words with concrete meanings. We examined event-related potentials (ERP) and applied independent component analysis (ICA) to find and separate simultaneously activated neural sources. Spectral analysis was also performed to investigate the gamma-band activity (GBA, 30-50 Hz) which is known to reflect feature binding. Five significant ERP components were identified and left hemispheric dominance was observed for most sites. Meaningful differences of amplitudes and latencies among languages were observed. It seemed that familiarity with each language and orthographic characteristics affected the characteristics of ERP components. ICA helped confirm several prominent sources corresponding to some ERP components. The results of spectral and time-frequency analyses showed distinct GBAs at prefrontal, frontal, and temporal sites. The GBAs at prefrontal and temporal sites were significantly correlated with the LPC amplitude and response time. The differences in spatiotemporal patterns of GBA among languages were not prominent compared to the inter-individual differences. The gamma-band coherence revealed short-range connectivity within frontal region and long-range connectivity between frontal, posterior, and temporal sites.

Keywords

References

  1. American Electroencephalographic Society, 'Guidelines for standard electrode position nomenclature,' J. Clin Neurophysiol, vol. 8, pp.200-202, 1991 https://doi.org/10.1097/00004691-199104000-00007
  2. J. T. Baker, A. L. Sanders, L. Maccotta, R. L. Buckner, 'Neural correlates of verbal memory encoding during semantic and structural processing tasks,' NeuroReport, vol. 12, pp.287-295, 2001
  3. S. Fu, Y. Chen, S. Smith, S. Iversen, P. M. Matthews, 'Effects of word form on brain processing of written Chinese,' Neurolmage, vol. 17, pp.1538-1548, 2002 https://doi.org/10.1006/nimg.2002.1155
  4. G. Gratton, M. G. Coles, E. Donchin, 'A new method of off-line removal ofocular artifact,' Electroencephalogr. Clin.Neurophysiol., vol. 55, pp.468-484, 1983 https://doi.org/10.1016/0013-4694(83)90135-9
  5. A. Khateb, J. -M. Annoni, T. Landis, A. J. Pegna, M. C. Custodi, E. Fonteneau, S. M. Morand, C. M. Michel, 'Spatio-temporal analysis of electric brain activity during semantic and phonological word processing,' Int. J. Psychophys., vol. 32, pp.215-231,1999 https://doi.org/10.1016/S0167-8760(99)00017-3
  6. K. Seki, N. Nakasato, S. Fujita, K. Hatanaka, T. Kawamura, A. Kanno, T. Yoshimoto, 'Neuromagnetic evidence that the P100 component of the pattern reversal visual evoked response originates in the bottom ofthe calcarine fissure,' Electroencephalogr. Clin.Neurophysiol., vol. 100, pp.436-442, 1996 https://doi.org/10.1016/0168-5597(96)95098-4
  7. K. Engel and W. Singer. 'Temporal binding and the neural correlates of sensory awareness,' Trends Cogn. Sci., vol. 5, pp.16-25,2001 https://doi.org/10.1016/S1364-6613(00)01568-0
  8. W. H. Miltner, C. Braun, M. Arnold, H. Witte, E. Taub., 'Coherence of gamma-band EEG activity as a basis for associative learning,' Nature, vol. 397, pp.434-6, 1999 https://doi.org/10.1038/17126
  9. M. M. Muller, T. Gruber, A. Keil., 'Modulation of induced gamma band activity in the human EEG by attention and visual information processing,' Int. J. Psychophys., vol. 38, pp.283-299, 2000 https://doi.org/10.1016/S0167-8760(00)00171-9
  10. H. W. Yoon, K. D. Cho, J. Y. Chung, H. Park, 'Neural mechanisms of Korean word reading: a functional magnetic resonance imaging study,' Neuroscience Letters, vol. 373 pp.206-211, 2005 https://doi.org/10.1016/j.neulet.2004.10.021
  11. N. E. Crone, D. L. Miglioretti, B. Gordon, R. P. Lesser. 'Functional mapping ofhuman sensorimotor cortex with electrocorticographic spectral analysis,' Brain, vol. 121, pp.2301-2315, 1998 https://doi.org/10.1093/brain/121.12.2301
  12. C. Eulitz, B. Maess, C. Pantev, A. D. Friederich, B. Feige, T. Elbert. 'Oscillatory neuromagnetic activity induced by language and non-language stimuli,' Brain Res. Cogn. Brain Res., vol. 4, pp.121-132,1996 https://doi.org/10.1016/0926-6410(96)00026-2
  13. M. Krause, P. Korpilahti, B. Porn, J. Jantti, H. A. Lang. 'Automatic auditory word perception as measured by 40 Hz EEG responses,' Electroencephalogr. Clin.Neurophysiol., vol. 107, pp.84-87, 1998 https://doi.org/10.1016/S0013-4694(98)00030-3
  14. F. Pulvermuller, C. Eulitz, C. Pantev, B. Mohr, B. Feige, W. Lutzenberger, T. Elbert, N. Birbaumer, 'High-frequency cortical responses reflect lexical processing: an MEG study,' Electroencephalogr. Clin. Neurophysiol., vol. 98, pp.76-85, 1996 https://doi.org/10.1016/0013-4694(95)00191-3
  15. T. P. Jung, S. Makeig, M. Westerfield, J. Townsend, E. Courchesne, T. J. Sejnowski, 'Analysis and visualization of single-trial event-related potentials,' Hum.Brain Mapp., vol. 14, pp.166-185, 2001 https://doi.org/10.1002/hbm.1050
  16. S. Makeig, A. Delorme, M. Westerfield, TP. Jung, J. Townsend, E. Courchesne, T. J. Sejnowski, 'Electroencephalographic brain dynamics following manuaily responded visual targets,' PLoS. Bioi., vol. 2, pp.747-762, 2004
  17. A. Delorme, S. Makeig, 'EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis,' J. Neurosci. Methods., vol. 134, pp.9-21, 2004 https://doi.org/10.1016/j.jneumeth.2003.10.009
  18. K. H. Kim, J. H. Kim, 'Comparison of spatiotemporal brain activation pattern during visual perception of Korean, English, Chinese words: an ERP study,' Neuroscience Letters, vol. 394, pp. 227-232, 2006 https://doi.org/10.1016/j.neulet.2005.10.101
  19. K. H. Kim, J. H. Kim, 'Analysis of Induced Gamma-band Activity in EEG during Visual Perception of Korean, English, Chinese Words,' submitted for publication, Neuroscience Letters, 2006
  20. Tarkiainen, P. Helenius, P. C. Hansen, P. L. Cornelissen, R. Salmelin, 'Dynamics of letter string perception in human occipitotemporal cortex,' Brain, vol. 122, pp.2119-2131, 1999 https://doi.org/10.1093/brain/122.11.2119
  21. S. Bentin, Y. Mouchetant-Rostaing, M. H. Giard, J. F. Echallier, J. Pernier, 'ERP manifestation of processing printed words at different psycholinguistic levels: time course and scalp distribution,' J. Cog. Neurosci., vol. 11, pp.235-260, 1999 https://doi.org/10.1162/089892999563373
  22. M. W. L. Chee, B. Weekes, K. M. Lee, C. S. Soon, A. Schreiber, J. J. Hoon, M. Chee, 'Overlap and dissociation of semantic processing of Chinese characters, English words, and pictures: evidence from fMRI,' Neurolmage, vol. 12, pp.392-403, 2000 https://doi.org/10.1006/nimg.2000.0631
  23. A. Khateb, A. J. Pegna, C. M. Michel, T. Landis, J. M. Annoni, 'Dynamics ofbrain activation during an explicit word and image recognition task: An electrophysiological study,' Brain Topogr., vol. 14, pp.197-213, 2002 https://doi.org/10.1023/A:1014502925003
  24. L. Cohen, S. Dehaene, L. Naccache, S. Lehericy, G. DehaeneLambertz, M. A. Henaff, F. Michel, 'The visual word form area, spatial and temporal characterization of an initial stage of reading in normal subjects and posterior split-brain patients,' Brain, vol. 123, pp.291-307, 2000 https://doi.org/10.1093/brain/123.2.291
  25. M. E. Smith., 'Neurophysiological manifestations ofrecollective experience during recognition memory judgments', J. Cog. Neurosci., vol. 5, pp.1-13, 1993 https://doi.org/10.1162/jocn.1993.5.1.1
  26. Y. Liu, C. A. Perfetti, 'The time course of brain activity in reading English and Chinese: an ERP study ofChinese bilinguals,' Hum. Brain Mapp., vol. 18, pp.167-175, 2003 https://doi.org/10.1002/hbm.10090
  27. S. Bentin, Y. Mouchetant-Rostaing, M. H. Giard, J. F. Echallier, J. Pernier, 'ERP manifestation of processing printed words at different psycholinguistic levels: time course and scalp distribution,' J. Cog. Neurosci., vol. 11, pp.235-260, 1999 https://doi.org/10.1162/089892999563373
  28. K. H. Kim, H. W. Yoon, H. W. Park, 'Spatiotemporal brain activation pattern during word/picture perception by native Koreans,' NeuroReport, vol. 15, pp.l099-1103, 2004 https://doi.org/10.1097/00001756-200401190-00020
  29. J. Niessing, B. Ebisch, K. E. Schmidt, M. Niessing, W. Singer, R. A. W. Galuske, 'Hemodynamic signals correlate tightly with synchronized gamma oscillations,' Science, vol. 309, pp.948-951, 2005 https://doi.org/10.1126/science.1110948
  30. N. Forss, T. Silen, T. KaIjalainen, 'Lack of activation of human secondary somatosensory cortex in Unverricht-Lundborg type of progressive myoclonus epilepsy,' Ann. Neurol., vol. 49, pp. 90-97,2001 https://doi.org/10.1002/1531-8249(200101)49:1<90::AID-ANA12>3.0.CO;2-D
  31. S. P. Fitzgibbon, K. 1 Pope, L. Mackenzie, C. R. Clark, J. O. Willoughby, 'Cognitive tasks augment gamma EEG power.' Clin. Neurophys., vol. 115, pp.1802-1809, 2004 https://doi.org/10.1016/j.clinph.2004.03.009
  32. A. K. MacLeod, R. L. Buckner, F. M. Miezin, S. E. Petersen, M. E. Raichle, 'Right anterior prefrontal cortex activation during semantic monitoring and working memory,' Neuroimage., vol.7, pp41-48,1998 https://doi.org/10.1006/nimg.1997.0308
  33. L. H. Tan, C. M. Feng, P. T. Fox, J. -H. Gao, 'An fMRI study with written Chinese,' NeuroReport, vol. 12, pp.83-88, 2001 https://doi.org/10.1097/00001756-200101220-00024
  34. M. Lepage, O. Ghaffar, L. Nyberg, E. Tulving, 'Prefrontal cortex and episodic memory retrieval mode,' in Proc. Nat!. Acad. Sci., vol. 97, pp.506-511, 2000
  35. M. Rose, T. Sommer, C. Buchel, 'Integration oflocal features to a global percept by neural coupling,' Cereb. Cortex., to be published, 2006
  36. E..Rodriguez, N. George, J.P. Lachaux, J. Martinerie, B. Renault, and F.J. Varela, 'Perception's shadow: long-distance synchronization of human brain activity', Nature, vol. 397, pp. 430-433,1999 https://doi.org/10.1038/17120
  37. S. P. Fitzgibbon, K. J Pope,L. Mackenzie, C. R. Clark and J. O. Willoughby, 'Cognitive tasks augment gamma EEG power', Clin. Neurophys., vol.115, pp. 1802-1809,2004 https://doi.org/10.1016/j.clinph.2004.03.009
  38. F. Varela, J. P. Lachaux, E. Rodriguez, J. Martinerie, 'The brainweb: Phase synchronization and large-scale integration', Nat. Rev. Neurosci., vol. 2, pp. 229-239,2001 https://doi.org/10.1038/35067550
  39. J. Sarnthein, H. Petsche, P. Rappelsberger, G. L. Shaw, A. von Stein, 'Synchronization between prefrontal and posterior association cortex during human working memory' in Proc. Natl. Acad. Sci. USA., vol. 95, pp. 7092-7096, 1997
  40. C. Babiloni, F. Vecchio, S. Cappa, P. Pasqualetti, S. Rossi, C. Miniussi, P.M. Rossini, 'Functional frontoparietal connectivity during encoding and retrieval processesfollows HERA model A high-resolution study,' Brain Res. Bull., vol. 68, pp. 203-12, 2006 https://doi.org/10.1016/j.brainresbull.2005.04.019