References
- Baluna, R., E. Coleman, C. Jones, V. Ghetie, and E. S. Vitetta. 2000. The effect of a monoclonal antibody coupled to ricin A chain-derived peptides on endothelial cells in vitro: Insights into toxin-mediated vascular damage. Exp. Cell. Res. 258: 417-424 https://doi.org/10.1006/excr.2000.4954
-
Bera, T. K. and I. Pastan. 1998. Comparison of recombinant immunotoxins against
$Le^Y$ antigen expressing tumor cells: Influence of affinity, size, and stability. Bioconjug. Chem. 9: 736-743 https://doi.org/10.1021/bc980028o - Brinkmann, U., L. H. Pai, D. J. FitzGerald, M. Willingham, and I. Pastan. 1991. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice. Proc. Natl. Acad. Sci. USA 88: 8616-8620
- Buchner, J., I. Pastan, and U. Brinkmann. 1992. A method for increasing the yield of properly folded recombinant fusion proteins: Single-chain immunotoxins from renaturation of bacterial inclusion bodies. Anal. Biochem. 205: 263-270 https://doi.org/10.1016/0003-2697(92)90433-8
- Buchner, J. and R. Rudolph. 1991. Renaturation, purification and characterization of recombinant Fab-fragments produced in Escherichia coli. Bio/Technology 9: 157-162 https://doi.org/10.1038/nbt0291-157
- Choe, M., K. O. Webber, and I. Pastan. 1994. B3(Fab)PE38M: A recombinant immunotoxin in which a mutant form of Pseudomonas exotoxin is fused to the Fab fragment of monoclonal antibody B3. Cancer Res. 54: 3460-3467
- Choi, S., J. Kim, Y. Lee, Y.-J. Jang, I. Pastan, and M. Choe. 2001. A divalent immunotoxin formed by the disulfide bond between hinge regions of Fab domain. Bull. Kor. Chem. Soc. 22: 1361-1365
- Dall' Acqua, W., A. L. Simon, M. G. Mulkerrin, and P. Carter. 1998. Contribution of domain interface residues to the stability of antibody CH3 domain homodimers. Biochemistry 37: 9266-9273 https://doi.org/10.1021/bi980270i
- Deonarain, M. P. and A. A. Epenetos. 1998. Design, characterization and anti-tumour cytotoxicity of a panel of recombinant, mammalian ribonuclease-based immunotoxins. Br. J. Cancer 77: 537-546 https://doi.org/10.1038/bjc.1998.87
- Hudson, P. J. 1999. Recombinant antibody constructs in cancer therapy. Curr. Opin. Immunol. 11: 548-557 https://doi.org/10.1016/S0952-7915(99)00013-8
- Hudson, P. J. and A. A. Kortt. 1999. High avidity scFv multimers; diabodies and triabodies. J. Immunol. Methods 231: 177-189 https://doi.org/10.1016/S0022-1759(99)00157-X
- Jurado, P., D. Ritz, J. Beckwith, V. de Lorenzo, and L. A. Fernandez. 2002. Production of functional single-chain Fv antibodies in the cytoplasm of Escherichia coli. J. Mol. Biol. 320: 1-10 https://doi.org/10.1016/S0022-2836(02)00405-9
- Kihara, A. and I. Pastan. 1995. Cytotoxic activity of chimeric toxins containing the epidermal growth factor-like domain of heregulins fused to PE38KDEL, a truncated recombinant form of Pseudomonas exotoxin. Cancer Res. 55: 71-77
- Kim, S. H. 2003. Expression and purification of recombinant immunotoxin -- a fusion protein stabilizes a single-chain Fv (scFv) in denaturing condition. Protein Expr. Purif. 27: 85-89 https://doi.org/10.1016/S1046-5928(02)00539-9
- Kreitman, R. J. 1999. Immunotoxins in cancer therapy. Curr. Opin. Immunol. 11: 570-578 https://doi.org/10.1016/S0952-7915(99)00005-9
- Kreitman, R. J., C. N. Chang, D. V Hudson, C. Queen, P. Bailon, and I. Pastan. 1994. Anti-Tac(Fab)-PE40, a recombinant double-chain immunotoxin which kills interleukin-2-receptor-bearing cells and induces complete remission in an in vivo tumor model. Int. J. Cancer 57: 856-864 https://doi.org/10.1002/ijc.2910570615
- Kreitman, R. J., I. Margulies, M. Stetler-Stevenson, Q. C. Wang, D. J. FitzGerald, and I. Pastan. 2000. Cytotoxic activity of disulfide-stabilized recombinant immunotoxin RFB4( dsFv)PE38 (BL22) toward fresh malignant cells from patients with B-cell leukemias. Clin. Cancer Res. 6: 1476-1487
- Kuan, C. T. and I. Pastan. 1996. Recombinant immunotoxin containing a disulfide-stabilized Fv directed at erbB2 that does not require proteolytic activation. Biochemistry 35: 2872-2877 https://doi.org/10.1021/bi952047g
- Kwak, B.-Y., B.-J. Kwon, C.-H. Kweon, and D.-H. Shon. 2004. Detection of Aspergillus, Penicillium, and Fusarium species by sandwich enzyme-linked immunosorbent assay using mixed monoclonal antibodies. J. Microbiol. Biotechnol. 14: 385-389
- Lawrence, L. J., A. A. Kortt, P. Iliades, P. A. Tulloch, and P. J. Hudson. 1998. Orientation of antigen binding sites in dimeric and trim eric single chain Fv antibody fragments. FEBS Lett. 425: 479-484 https://doi.org/10.1016/S0014-5793(98)00292-0
- Lee, J.-W, I.-J. Jun, H. J. Kwun, K. L. Jang, and J. Cha. 2004. Direct identification of Vibrio vulnificus by PCR targeting elastase gene. J. Microbiol. Biotechnol. 14: 284-289
- Lim, H.-K., S.-U. Lee, S.-I. Chung, K.-H. Jung, and J.-H. Seo. 2004. Induction of the T7 promoter using lactose for production of recombinant plasminogen Kringle 1-3 in Escherichia coli. J. Microbiol. Biotechnol. 14: 225-230
- Mansfield, E., P. AmIot, I. Pastan, and D. J. FitzGerald. 1997. Recombinant RFB4 immunotoxins exhibit potent cytotoxic activity for CD22-bearing cells and tumors. Blood 90: 2020-2026
- Miller, K., G. Meng, J. Liu, A. Hurst, V. Hsei, W. L. Wong, R. Ekert, D. Lawrence, S. Sherwood, L. DeForge, J. Gaudreault, G. Keller, M. Sliwkowski, A. Ashkenazi, and L. Presta. 2003. Design, construction, and in vitro analyses of multivalent antibodies. J. lmmunol. 170: 4854-4861
- Onda, M., Q. C. Wang, H. F. Guo, N. K. Cheung, and I. Pastan. 2004. In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma. Cancer Res. 15: 1419-1424
- Pai, L. H., R. Wittes, A. Setser, M. C. Willingham, and I. Pastan. 1996. Treatment of advanced solid tumors with immunotoxin LMB-1: An antibody linked to Pseudomonas exotoxin. Nat. Med. 2: 350-353 https://doi.org/10.1038/nm0396-350
- Park, J. H., H. W. Kwon, H. K. Chung, I. H. Kim, K. Ahn, E. J. Choi, I. Pastan, and M. Choe. 2001. A divalent recombinant immunotoxin formed by a disulfide bond between the extension peptide chains. Mol. Cells 12: 398-402
- Park, S. S., C. J. Ryu, Y. J. Kang, S. V. Kashmiri, and H. J. Hong. 2000. Generation and characterization of a novel tetravalent bispecific antibody that binds to hepatitis B virus surface antigens. Mol. Immunol. 37: 1123-1130 https://doi.org/10.1016/S0161-5890(01)00027-X
- Pastan, I. 2003. Immunotoxins containing Pseudomonas exotoxin A: A short history. Cancer Immunol. Immunother. 52: 338-341
- Rajagopal, V., I. Pastan, and R. J. Kreitman. 1997. A form of anti-Tac(Fv) which is both single-chain and disulfide stabilized: Comparison with its single-chain and disulfidestabilized homologs. Protein Eng. 10: 1453-1459 https://doi.org/10.1093/protein/10.12.1453
- Reiter, Y., U. Brinkmann, K. O. Webber, S. H. Jung, B. Lee, and I. Pastan. 1994. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: Improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv. Protein Eng 7: 697-704 https://doi.org/10.1093/protein/7.5.697
- Reiter, Y., L. H. Pai, U. Brinkmann, Q. C. Wang, and I. Pastan. 1994. Antitumor activity and pharmacokinetics in mice of a recombinant immunotoxin containing a disulfide-stabilized Fv fragment. Cancer Res. 54: 2714-2718
- Reiter, Y. and I. Pastan. 1998. Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis. Trends Biotechnol. 16: 513-520 https://doi.org/10.1016/S0167-7799(98)01226-8
- Reiter, Y., A. F. Wright, D. W. Tonge, and I. Pastan. 1996. Recombinant single-chain and disulfide-stabilized Fv immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice. Int. J. Cancer 67: 113-123 https://doi.org/10.1002/(SICI)1097-0215(19960703)67:1<113::AID-IJC19>3.0.CO;2-F
- Ridgway, J. B., L. G. Presta, and P. Carter. 1996. 'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization. Protein Eng. 9: 617 -621 https://doi.org/10.1093/protein/9.7.617
- Schmiedl, A., F. Breitling, and S. Dubel. 2000. Expression of a bispecific dsFv-dsFv' antibody fragment in Escherichia coli. Protein Eng. 13: 725-734 https://doi.org/10.1093/protein/13.10.725
- Shim, Y-Y, D.-H. Shon, B.-Y. Kwak, J. Yu, and K.-M. Chee. 2004. Comparison of properties of poly clonal anti-N-acetylchitooligosaccharides and anti-chitooligosaccharides antibodies produced for ELISA. J. Microbiol. Biotechnol. 14: 686-692
- Todorovska, A., R. C. Roovers, O. Dolezal, A. A. Kortt, H. R. Hoogenboom, and P. J. Hudson. 2001. Design and application of diabodies, triabodies and tetrabodies for cancer targeting. J. Immunol. Methods 248: 47-66 https://doi.org/10.1016/S0022-1759(00)00342-2