The Journal of Korean Physical Therapy

  • 제18권1호
  • /
  • Pages.65-73
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  • 2006
  • /
  • 1229-0475(pISSN)
  • /
  • 2287-156X(eISSN)
대한물리치료학회 (The Korean Society of Physical Therapy)
권호 표지

전침자극과 경피신경전기자극이 흰쥐 좌골신경 압좌손상 후 척수내 GAP-43 발현에 미치는 영향

The Effect of EA and TENS on GAP-43 Expression in Spinal Cord after Rat Sciatic Nerve Crush Injury

  • 이현민 (대구대학교 대학원 재활과학과 물리치료) ;
  • 박은세 (대구대학교 대학원 재활과학과 물리치료) ;
  • 김민희 (대구대학교 대학원 재활과학과 물리치료) ;
  • 김석범 (제주한라대학 작업치료과) ;
  • 김동현 (서라벌대학교 작업치료과) ;
  • 김진상 (대구대학교 재활과학대학 물리치료학과)
  • Lee, Hyun-Min (Major in Physical Therapy, Department of Rehabilitation Science, Graduate school of Daegu University) ;
  • Park, Eun-Se (Major in Physical Therapy, Department of Rehabilitation Science, Graduate school of Daegu University) ;
  • Kim, Min-Hee (Major in Physical Therapy, Department of Rehabilitation Science, Graduate school of Daegu University) ;
  • Kim, Souk-Boum (Department of Occupational Therapy, Cheju Halla College) ;
  • Kim, Dong-Hyun (Department of Occupational Therapy, Sorabol College) ;
  • Kim, Jin-Sang (Department of Physical Therapy, College of Rehabilitation Science, Daegu University)
  • 발행 : 2006.02.24
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초록

Purpose: The purpose of this study was to identify the effect of electroacupuncture(EA) and transcutaneous electric nerve stimulation(TENS) after sciatic nerve crush injury in rats. Methods: The EA for experimental group I (Exp I, n=15) and TENS for experimental group II (Exp II, n=15) was applied from post-injury day(PD) 1 to PD 14 after sciatic nerve injury using low frequency stimulator that gave electrical stimulation(15min/60Hz). In order observe the effect of EA and TENS, this study examined GAP-43 expression in rat lumbar spinal cord at the PD 1, PD 7 and PD 14. In addition, the stride length(SL) and toe out angle(TOA) were measured at the PD 7 and PD 4. Results; Exp I and Exp II had higher GAP-43 immunoreactivity than control group(PD 1, 7, 14). The SL of Exp I and Exp II were significantly higher than control group(PD 7, 14). The TOA of Exp I and Exp II were significantly lower than control group(PD 7, 14). Conclusion: EA and TENS application increased motor nerve recovery and expression of GAP-43 immunoreactivity after sciatic nerve crush injury. Therefore effect of TENS and EA had similar effect on nerve regeneration and functional recovery.

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