A Comparison of Iopamidol with Iopromide and Iohexol Contrast Media in Hepatic CT Angiography in Beagle Dogs

비글견의 간 CT 혈관조영상에서의 Iopamidol과 Iopromide, Iohexol 조명제의 비교실험

  • Jeong Yu-Cheol (College of Veterinary Medicine, Seoul National University) ;
  • Lim Chang-Yun (College of Veterinary Medicine, Seoul National University) ;
  • Kim Gyeong-Min (College of Veterinary Medicine, Seoul National University) ;
  • Lee Sung-Ok (College of Veterinary Medicine, Seoul National University) ;
  • Jung Joo-Hyun (College of Veterinary Medicine, Seoul National University) ;
  • Chang Jin-Hwa (College of Veterinary Medicine, Seoul National University) ;
  • Oh Sun-Kyoung (College of Veterinary Medicine, Seoul National University) ;
  • Song Kyoung-Jin (College of Veterinary Medicine, Seoul National University) ;
  • Yoon Jung-Hee (College of Veterinary Medicine, Seoul National University) ;
  • Choi Min-Cheol (College of Veterinary Medicine, Seoul National University)
  • 정유철 (서울대학교 수의과대학 수의학과) ;
  • 임창윤 (서울대학교 수의과대학 수의학과) ;
  • 김경민 (서울대학교 수의과대학 수의학과) ;
  • 이성옥 (서울대학교 수의과대학 수의학과) ;
  • 정주현 (서울대학교 수의과대학 수의학과) ;
  • 장진화 (서울대학교 수의과대학 수의학과) ;
  • 오선경 (서울대학교 수의과대학 수의학과) ;
  • 송경진 (서울대학교 수의과대학 수의학과) ;
  • 윤정희 (서울대학교 수의과대학 수의학과) ;
  • 최민철 (서울대학교 수의과대학 수의학과)
  • Published : 2006.06.01

Abstract

The purpose of this paper was to compare the clinical efficacy of iopamidol and iopromide, iohexol nonionic contrast media in terms of their image quality in Beagle dogs with hepatic CT angiography and their application in veterinary clinics. With 9 Beagle dogs, contrast media of iopamidol (pamiray-$300^(R)$) and iopromide (ultravist-$300^(R)$, iohexol (omnipaque-$300^(R)$) were induced intravenously (600 mg I/kg, BW) and CT angiography was done under general anesthesia. CT scan included scout, pre-contrast and cine examinations. During CT angiography, peak HU (Hounsfield unit) and peak time were examined on each site (ROI; region of interest) of the aorta, caudal vena cava, potral vein and liver parenchyma. Any side effects were also examined. After experiments, it was found that there were no significant changes of HU and maximal enhancing time of each ROIs of aorta, caudal vena cava, portal vein and liver parenchyma between these contrast media. And any side effects were not noted. So it is concluded that iopamidol has similiar contrast enhancement like as iopromide and iohexol in hepatic angiography and and it is thought to be useful for evaluation of the abdominal organs by CT scan in veterinary clinics.

Keywords

References

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