대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제27권3호
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- Pages.617-628
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- 2006
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- 1226-9174(pISSN)
고cholesterol 식이 자발성 고혈압 백서(白鼠)에서의 가미방풍통성산(加味防風通聖散)이 고혈압에 미치는 영향
Effects of Kamibangpungtongsungsan on Hypertension in Spontaneous Hypertensive Rats Fed a Hyperlipidemic Diet
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김종원
(대전대학교 한의과대학 내과학교실) ;
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조현경
(대전대학교 한의과대학 내과학교실) ;
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유호룡
(대전대학교 한의과대학 내과학교실) ;
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설인찬
(대전대학교 한의과대학 내과학교실) ;
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김윤식
(대전대학교 한의과대학 내과학교실)
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Kim, Jong-Won
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Jo, Hyun-Kyung
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Yoo, Ho-Rhyong
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Seol, In-Chan
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
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Kim, Yoon-Sik
(Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
- 발행 : 2006.09.30
초록
This experiment was performed to determine the effects of Kamibangpungtongsungsan on hypertension in spontaneous hypertensive rats fed a hyperlipidemic diet (H-SHR). The results are summarized as follows : 1. Kamibangpungtongsungsan significantly decreased the blood pressure and pulse of rats in H-SHR. 2. Kamibangpungtongsungsan significantly decreased the levels of Aldosterone in H-SHR. 3. Kamibangpungtongsungsan significantly decreased the levels of dopamine and epinephrine in H-SHR, but did not significantly reduce the levels of norepinephrine, in H-SHR. 4. Kamibangpungtongsungsan did not significantly reduce the levels of electrolytes in H-SHR. 5. Kamibangpungtongsungsan significantly decreased the TNF-