대한한방내과학회지 (The Journal of Internal Korean Medicine)

대한한방내과학회 (The Society of Internal Korean Medicine)
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항암제로 유발된 백혈구감소증 회복에 미치는 황기의 효과

The Effects of Astragali Radix on Cyclophosphamide-induced Leukocytopenia

  • 한인선 (유민한방병원 내과) ;
  • 김병우 (상지대학교 한의과대학 내과학교실)
  • Han, In-Sun (Yumin Hospital of Oriental Medicine) ;
  • Kim, Byoung-Woo (Department of Internal Medicine, Oriental Hospital of Sangji University)
  • 발행 : 2006.09.30
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초록

Objective : This study was performed to investigate the effect of Astragali Radix on leukocytopenia anaphysis with carcinostatic substance elicitation. Methods : We observe if there were differences in a general tendency by EAR (AR extracts) capacity in the Astragali Radix treated group and the cyclophosphamide treated group, a general tendency of recovery from leukocytopenia over lime and checked for liver and kidney toxicity. Results : In cyclophosphamide treated with EAR 1000mg/kg group, the recovery rate of leukocytopenia increased and there were no differences in liver and kidney functions. Conclusions : Astragali Radix was effective and safe in increasing rate of leukocytopenia anaphysis with carcinostatic substance elicitation and indicated possibility for clinically adaptation.

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