Follicular Thyroid Carcinoma Associated with Macroscopic Vascular Invaion and Intraluminal Tumor Thrombosis in Great Cervical Veins : Two Case Reports

경부의 주정맥 침범과 암성 혈전을 보인 여포상 갑상선암 2예

  • Lim Jun-Sup (Department of Surgery, Yonsei University College of Medicine) ;
  • Lee Jan-Dee (Department of Surgery, Yonsei University College of Medicine) ;
  • Yun Ji-Sup (Department of Surgery, Yonsei University College of Medicine) ;
  • Lim Chi-Young (Department of Surgery, Yonsei University College of Medicine) ;
  • Nam Kee-Hyun (Department of Surgery, Yonsei University College of Medicine) ;
  • Chang Hang-Seok (Department of Surgery, Yonsei University College of Medicine) ;
  • Chung Woong-Youn (Department of Surgery, Yonsei University College of Medicine) ;
  • Park Cheong-Soo (Department of Surgery, Yonsei University College of Medicine)
  • 임준섭 (연세대학교 의과대학 외과학교실) ;
  • 이잔디 (연세대학교 의과대학 외과학교실) ;
  • 윤지섭 (연세대학교 의과대학 외과학교실) ;
  • 임치영 (연세대학교 의과대학 외과학교실) ;
  • 남기현 (연세대학교 의과대학 외과학교실) ;
  • 장항석 (연세대학교 의과대학 외과학교실) ;
  • 정웅윤 (연세대학교 의과대학 외과학교실) ;
  • 박정수 (연세대학교 의과대학 외과학교실)
  • Published : 2006.05.01

Abstract

Differentiated thyroid carcinomas are rarely associated with macroscopic vascular invasion and intraluminal tumor thrombus in great cervical veins. The best treatment for such cases appears to be a total thyroidectomy with en-block resection of the involved vessels, followed by postoperative radioiodine therapy(RI). We report two cases of follicular thyroid carcinoma with vascular invasion and intraluminal tumor thrombosis in great cervical veins that were successfully treated using complete surgical resection and postoperative RI.

Keywords

References

  1. Holt WL: Extension of malignant tumors of thyroid into great veins and heart. JAMA. 1934;102(19):21-24 https://doi.org/10.1001/jama.1934.02750010021005
  2. Jern-Lin L, Jeng WY, Virginia AL, et al: Insular carcinoma of the thyroid with jugular vein invasion. Head Neck. 2004;26:642-646 https://doi.org/10.1002/hed.20037
  3. Anjali M, Amit A, Gaurav A, et al: Internal jugular vein invasion by thyroid carcinoma. Eur J Surg. 2001;167:64-67 https://doi.org/10.1080/110241501750069855
  4. Lalak NJ, Cambell PR Infiltrating papillary carcinoma of the thyroid with macroscopic extesion into the internal jugular vein. Otolaryngol Head Neck Surg. 1988;117 (61):1-6 https://doi.org/10.1016/S0194-5998(97)70198-0
  5. Sengupta S, Kalkonde Y, Khot R, et al: Idiopathic bilateral external jugular vein thrombosis: a case report. Angiology. 2001;52: 69-71 https://doi.org/10.1177/000331970105200110
  6. Onran Y, Terzioglu T, Oguz H, et al: Great cervical vein invasion by thyroid cancer. Thyroid. 1998;8:59-61 https://doi.org/10.1089/thy.1998.8.59
  7. Eisuke K, Hiroyuki Y, Shin W, et al: Brachiocephalic vein thrombus of papillary thyroid cancer: Report of a case. Surg Today. 2002; 32:59-62 https://doi.org/10.1007/s595-002-8114-7
  8. Menachem G, Yoav M, Bella M, et al: 1nternal jugular vein tumor thrombus associated with thyroid carcinoma. Ann Otol Rhinol Laryngol. 2004;113.134-740
  9. Perez D, Brown L: Follicular carcinoma of the thyroid appearing as an intraluminal superior vena cava tumor. Arch Surg. 1984; 119:324-326
  10. Thompson NW, Brown J, Orringer M, et al: Follicular carcinoma of the thyroid with massive angioinvasion: Extension of tumor thrombus to the heart. Surgery. 1978;83:451-457
  11. Sakamoto A, Kassai N, Sugano H et al: Poorly differentiated carcinoma of the thyroid. A clinicopathoologic entity for the high-risk group of papillary and follicular carcinom, Cancer. 1983; 52:1845-1855
  12. Thomas S, Sawhney S, Kapur BM: Case report: Bilateral massive internal jugular vein thrombosis in carcinoma of the thyroid: CT evaluation. Clin Radiol. 1992;43:433-434 https://doi.org/10.1016/S0009-9260(05)80580-X
  13. Bussani R, Silvestri F: Neoplastic thrombotic endocarditis of the tricuspid valve in a patient with carcinoma of the thyroid: Report of case. Pathol Res Tract. 1999;195:121-124 https://doi.org/10.1016/S0344-0338(99)80084-3
  14. Onaran Y, Terzioglu T, Oguz R, et a1: Great cervical vein invasion of thyroid carcinoma. Thyroid. 1998;8:59-61 https://doi.org/10.1089/thy.1998.8.59
  15. Clark OH: Locally advanced differentiated thyroid cancer. Surg Oncol. 2003;12:91-99 https://doi.org/10.1016/S0960-7404(03)00032-X
  16. Niederle B: Intraatrial extension of thyroid cancer: technique and results of a radical surgical approach. Surgery. 1990;108:951-956
  17. Yosem DM: Carotid artery invasion by head and neck masses: prediction with MR imaging. Radiology. 1995;195:715-720 https://doi.org/10.1148/radiology.195.3.7754000
  18. Thomas S, Sawhney S, Kapur BM: Case report: bilateral massive internal jugular vein thrombosis in carcinoma of the thyroid: et evaluation. Clin Radiol. 1991;43:433-434 https://doi.org/10.1016/S0009-9260(05)80580-X
  19. Farahati J, Reiners C, Stuschke M: Differentiated thyroid cancer: impact of adjuvant external radiotherapy in patients with perithy-roidal tumor infiltrations (stage pT4). Cancer. 1996;77:172-180 https://doi.org/10.1002/(SICI)1097-0142(19960101)77:1<172::AID-CNCR28>3.0.CO;2-1
  20. Mazzaferri EL, Young RL: Papillary thyroid carcinoma. A ten year follow up on impact of therapy in 576 patients. Am J Med. 1981;70:511-518 https://doi.org/10.1016/0002-9343(81)90573-8