A Case of Granular Cell Tumor of the Thyroid

갑상선에 발생한 과립세포종양 1예

  • Park Jong-Hoon (Department of Surgery, Chonnam National University Medical School) ;
  • Kang Hyo (Department of Surgery, Chonnam National University Medical School) ;
  • Cho Mun-Hyeong (Department of Surgery, Chonnam National University Medical School) ;
  • Yoon Jung-Han (Department of Surgery, Chonnam National University Medical School) ;
  • JaeGal Young-Jong (Department of Surgery, Chonnam National University Medical School) ;
  • Park Min-Ho (Department of Surgery, Chonnam National University Medical School)
  • 박종훈 (전남대학교 의과대학 외과학교실) ;
  • 강효 (전남대학교 의과대학 외과학교실) ;
  • 조문형 (전남대학교 의과대학 외과학교실) ;
  • 윤정한 (전남대학교 의과대학 외과학교실) ;
  • 제갈영종 (전남대학교 의과대학 외과학교실) ;
  • 박민호 (전남대학교 의과대학 외과학교실)
  • Published : 2006.05.01

Abstract

Granular cell tumor is not rare and is a well recognized entity which has a wide anatomic distribution, with roughly one half of the lesions found in the head and neck. However, occurrence in the thyroid is extremely rare and has not been described well as surgeon's view. The authors have recently experienced a case of multifocal granular cell tumor of the thyroid in a 26-year-old women presented with painless mass in the anterior neck area and fatigue. So, we present this case with the review of literatures.

Keywords

References

  1. Enzinger FM, Weiss SW: Soft tissue tumors. 3rd ed. St. Louis: Mosby. 1995:864-871
  2. Fisher ER, Wechsler H: Granular cell myoblasoma-a misnomer. electron microscopic and histocheical evidence concerning its Schwann cell derivation and nature (Granular cell Schwannoma). Cancer. 1962;15:936-954 https://doi.org/10.1002/1097-0142(196209/10)15:5<936::AID-CNCR2820150509>3.0.CO;2-F
  3. Miettinen M, Lehtonen E, Lehtola H, Ekblom P, Lehto VP, Virtanen I: Histogenesis of granular cell tumor-an immunohistochemical and ultrastructual study. J Pathol. 1984;142:221-229 https://doi.org/10.1002/path.1711420309
  4. Sobel NJ, Schwarz R, Marquert E: Light and electron microscopic study of the origin of granular cell myoblastoma. J Pathol. 1973;109:101-111 https://doi.org/10.1002/path.1711090204
  5. Pour P, Althoff J, Cardesa A: Granular cells in tumors and nontumorous tissue. Arch Pathol. 1973;95:135-138
  6. Armin A, Connelly EM, Rowden G: An immunoperoxidase investigation of S-100 protein in granular cell myoblastoma: evidence for Schwann cell derivation. Am J Clin Pathol. 1983;79: 37-44 https://doi.org/10.1093/ajcp/79.1.37
  7. Ulrich J, Heitz PHU, Fiswcher T, Obrist E, Gullotta F: Granular cell tumor: evidence of heterogeneous tumor cell differentiation. An immunohistochemical study. Virchows Arch B. 1987;53:52-57 https://doi.org/10.1007/BF02890224
  8. Mahoney CP, Patterson SD, Ryan J: Granular tumor of the thyroid gland in a girl receiving high dose estrogen therapy. Pediatr Pathol Lab Med. 1995;15:791-795 https://doi.org/10.3109/15513819509027014
  9. Suzanne M, Paproski SM, Owen DA: Grnular cell tumor of the thyroid. Arch Pathol Lab Med. 2001;125 (4):544-546
  10. Fanburg-Smith JC, Meis-Kinblom JM, Fante R, Kindblom LG: Malignant granular cell tumor of soft tissue: diagnostic criteria and clinicopathologic correlation. Am J Surg Pathol. 1998;22 (7): 779-794 https://doi.org/10.1097/00000478-199807000-00001
  11. Cutis BV, Calcatena TC, Coulson WF: Multiple granular cell tumor: a case report and review of the literature. Head Neck. 1997;19 (7):634-637 https://doi.org/10.1002/(SICI)1097-0347(199710)19:7<634::AID-HED12>3.0.CO;2-2
  12. Kang HJ, Hong EK, Park MH, Lee JD: Granular cell tumor of the thyroid. Korean J Pathol. 1998;32:63-67
  13. Brady PG, Nord HJ, Connar RG: Granular cell tumor of the esophagus: natural history, diagnosis, and therapy. Digestive Diseases and Sciednces. 1988;33:1329-1333 https://doi.org/10.1007/BF01536687
  14. Coutinho DS, Soga J, Yoshikawa T, et al: Granular cell tumors of the esophagus; A report of two cases and review of the literature. Am J Gastroenterol. 1985;80:758-762
  15. Tune JM, Bowles MH, Grunow W, Patel GK, Texter EC: Granular cell myoblastoma of the esophagus. Am J Gastroecnterol. 1981;75:426-430
  16. Erlandson RA: Diagnostic transmission electron micorscopy of tumors. New York: Raven Press, 1994:398-401
  17. Mscovic EA, Azam HA: Multiple granular cell tumors ('myoblastoma'): case report with electron microscopic observation and review of the literature. Cancer. 1967;20:2032-2047 https://doi.org/10.1002/1097-0142(196711)20:11<2032::AID-CNCR2820201133>3.0.CO;2-W