흡입화상 치료과정에서 생긴 공동성 폐 병변

A Case of Cavitary Lung Lesion as a Consequence of Smoke Inhalation Injury

  • 신현원 (한림대학교 의과대학 내과학교실) ;
  • 김철홍 (한림대학교 의과대학 내과학교실) ;
  • 엄광석 (한림대학교 의과대학 내과학교실) ;
  • 박용범 (한림대학교 의과대학 내과학교실) ;
  • 장승훈 (한림대학교 의과대학 내과학교실) ;
  • 김동규 (한림대학교 의과대학 내과학교실) ;
  • 이명구 (한림대학교 의과대학 내과학교실) ;
  • 현인규 (한림대학교 의과대학 내과학교실) ;
  • 정기석 (한림대학교 의과대학 내과학교실) ;
  • 이일성 (한림대학교 의과대학 영상의학과)
  • Shin, Hyun Won (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Kim, Cheol Hong (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Eom, Kwang Seok (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Park, Yong Bum (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Jang, Seung Hun (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Kim, Dong Gyu (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Lee, Myung Goo (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Hyun, In-Gyu (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Jung, Ki-Suck (Department of Internal Medicine, Hallym University College of Medicine) ;
  • Lee, Eil Seong (Department of Radiology, Hallym University College of Medicine)
  • 투고 : 2006.03.10
  • 심사 : 2006.04.28
  • 발행 : 2006.05.30

초록

화상환자에서의 흡입화상은 이환률 및 사망률에 영향을 미치는 중요한 인자이다. 호흡기계의 손상은 침범 부위 및 정도에 따라 매우 다양하게 나타나는데, 기도 손상의 경우 성문하 협착 등의 기도폐색을 일으킬 수 있으며, 폐실질의 손상은 저산소증, 폐렴, 호흡부전 및 급성호흡곤란증후군의 병태생리를 제공하게 된다. 흡입화상의 초기 방사선소견으로는 정상, 경화, 기관지주위 비후, 심인성 및 비심인성 폐부종, 무기폐, 간질성 혹은 폐포성 폐 침윤의 형태로 나타날 수 있다. 후기 변화로는 기관지확장증, 폐쇄 기관지염 및 폐 섬유화 등이 증례 보고된 바 있다. 하지만 성인 흡입화상 환자에서의 공동성 병변에 대해서는 보고 된 바 없다. 저자들은 44세 남자로 얼굴 및 양손에 9%의 경미한 피부 화염화상을 입었으나 흡입화상으로 인한 호흡기 합병증에 대한 치료가 더 중요시 되었던 환자로 치료 과정에서 좌상엽의 공동성 병변을 관찰하게 되었다. 추적 과정에서 이 공동은 계속 변화하는 양상이었으며 한차례 대량 객혈이 있었으나 그 후로는 다른 호흡기계 합병증 없이 저절로 소실해 가는 과정을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Toxic gases and soot deposition as a consequence of smoke inhalation can cause direct injury to the upper and lower airways and even to the lung parenchyma. A delay in proper and prompt therapy can be detrimental to critically ill burn patients with an inhalation injury. Therefore, serial chest radiography is an important diagnostic tool for pulmonary complications during treatment. The radiographic findings of the chest include normal, consolidation, interstitial and alveolar infiltrates, peribronchial thickening, atelectasis, cardiogenic and non-cardiogenic pulmonary edema, and a pneumothorax as acute complications of smoke inhalation. In addition, bronchiectasis, bronchiolitis obliterans and pulmonary fibrosis can occur as late complications. We encountered a case of 44-year-old male who presented with acute lung injury after an inhalation injury. He required endotracheal intubation and mechanical ventilation due to respiratory failure. He was managed successfully with conservative treatment. Later, a cavitary lesion of the left upper lobe was observed on the chest radiography and computed tomography, which was complicated by massive hemoptysis during the follow-up. However, the cavitary lesion disappeared spontaneously without any clinical consequences.

키워드

참고문헌

  1. Herndon DN, Gore D, Cole M, Desai MH, Linares H, Abston S, et al. Determinants of mortality in pediatric patients with greater than 70% full-thickness total body surface area thermal injury treated by early total excision and grafting. J Trauma 1987;27:208-12 https://doi.org/10.1097/00005373-198702000-00020
  2. Saffle JR, Davis B, Williams P. Recent outcomes in the treatment of burn injury in the United States: a report from the American Burn Association Patient Registry. J Burn Care Rehabil 1995;16:219-32 https://doi.org/10.1097/00004630-199505000-00002
  3. Shirani KZ, Pruitt BA Jr, Mason AD Jr. The influence of inhalation injury and pneumonia on burn mortality. Ann Surg 1987;205:82-7 https://doi.org/10.1097/00000658-198701000-00015
  4. Moylan JA Jr, Wilmore DW, Mouton DE, Pruitt BA Jr. Early diagnosis of inhalation injury using 133 xenon lung scan. Ann Surg 1972;176:477-84 https://doi.org/10.1097/00000658-197210000-00005
  5. Putman CE, Loke J, Matthay RA, Ravin CE. Radiographic manifestations of acute smoke inhalation. AJR Am J Roentgenol 1977;129:865-70 https://doi.org/10.2214/ajr.129.5.865
  6. Aberle DR, Brown K. Radiologic considerations in the adult respiratory distress syndrome. Clin Chest Med 1990;11:737-54
  7. George A, Gupta R, Bang RL, Ebrahim MK. Radiological manifestation of pulmonary complications in deceased intensive care burn patients. Burns 2003;29:73-8 https://doi.org/10.1016/S0305-4179(02)00201-2
  8. Lee MJ, O'Connell DJ. The plain chest radiograph after acute smoke inhalation. Clin Radiol 1988;39:33-7 https://doi.org/10.1016/S0009-9260(88)80334-9
  9. Teixidor HS, Novick G, Rubin E. Pulmonary complications in burn patients. J Can Assoc Radiol 1983;34:264-70
  10. Wittram C, Kenny JB. The admission chest radiograph after acute inhalation injury and burns. Br J Radiol 1994;67:751-4 https://doi.org/10.1259/0007-1285-67-800-751
  11. Slutzker AD, Kinn R, Said SI. Bronchiectasis and progressive respiratory failure following smoke inhalation. Chest 1989;95:1349-50 https://doi.org/10.1378/chest.95.6.1349
  12. Tasaka S, Kanazawa M, Mori M, Fujishima S, Ishizaka A, Yamasawa F, et al. Long-term course of bronchiectasis and bronchiolitis obliterans as late complication of smoke inhalation. Respiration 1995;62:40-2 https://doi.org/10.1159/000196386
  13. Chrysopoulo MT, Barrow RE, Muller M, Rubin S, Barrow LN, Herndon DN. Chest radiographic appearances in severely burned adults: a comparison of early radiographic and extravascular lung thermal volume changes. J Burn Care Rehabil 2001;22:104-10 https://doi.org/10.1097/00004630-200103000-00004
  14. Lee SH, Lee ES, Kim SH, Park JY, Kim SH, Hong SH, et al. Plain chest radiographic findings of smoke inhalation. J Korean Radiol Soc 2000;42:933-7 https://doi.org/10.3348/jkrs.2000.42.6.933
  15. George A, Bang RL, Gupta R, Khalaf EM. Minor burns and pneumatocoeles: a case report. Burns 2001;27:504-8 https://doi.org/10.1016/S0305-4179(00)00153-4