Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지

Clinical Characteristics of Lung Cancer Diagnosed in Chonnam National University Hospital(CNUH) Since 2000

전남대학교 병원에서 2000년 이후 진단된 폐암의 임상 특성

  • Lim, Jung Hwan (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Ban, Hee Jung (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Oh, In Jae (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Soo Ok (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Son, Jun Gwang (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Jeong, Jong Pil (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Kyu Sik (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Yu Il (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Lim, Sung Chul (Department of Internal Medicine, Chonnam National University Medical School) ;
  • Kim, Young Chul (Department of Internal Medicine, Chonnam National University Medical School)
  • 임정환 (전남대학교 의과대학 내과학교실) ;
  • 반희정 (전남대학교 의과대학 내과학교실) ;
  • 오인재 (전남대학교 의과대학 내과학교실) ;
  • 김수옥 (전남대학교 의과대학 내과학교실) ;
  • 손준광 (전남대학교 의과대학 내과학교실) ;
  • 정종필 (전남대학교 의과대학 내과학교실) ;
  • 김규식 (전남대학교 의과대학 내과학교실) ;
  • 김유일 (전남대학교 의과대학 내과학교실) ;
  • 임성철 (전남대학교 의과대학 내과학교실) ;
  • 김영철 (전남대학교 의과대학 내과학교실)
  • Received : 2006.08.23
  • Accepted : 2006.10.13
  • Published : 2006.11.30
Download PDF
⟨ Previous Next ⟩

Abstract

Background: Lung cancer has been the leading cause of cancer death in South Korea since 2000. This study examined the clinical characteristics of lung cancer patients diagnosed in a community hospital from the year 2000 to 2005, and compared these results with previously reported statistical data. Method: The lung cancer data in a form of an electronic medical record was downloaded from the hospital medical information system. The clinical characteristics of the 1,509 patients with lung cancer were analyzed retrospectively. Result: The mean age of the patients was 63.7 years. 82.5% and 74.5% of the patients were men and smokers, respectively. Squamous cell carcinoma (41.6%) was the most common pathology type followed by adenocarcinoma(32.3%) and small cell carcinoma(13.9%). When 604 patients who were diagnosed from 2000 to 2003 were compared with 905 patients diagnosed from 2004 to 2005, the age of patients increased significantly (61.5 years vs. 65.1 years; p<0.001) and the proportion of adenocarcinomas was significantly higher(29.3% vs. 34.4%; p=0.046). Conclusion: Among the major histology types of lung cancer, the incidence of adenocarcinoma has been increasing recently. The age of the lung cancer patients at diagnosis is getting older. This is despite the fact that the distributions of the initial anatomic stages have not changed significantly.

Keywords

References

  1. Korea National Statistical Office. 2004 Death rate statistics of Korea. 2005
  2. Wynder EL, Muscat JE. The changing epidemiology of smoking and lung cancer histology. Environ Health Perspect 1995;103:143-8 https://doi.org/10.1289/ehp.95103s8143
  3. Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, Brannigan BW, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39 https://doi.org/10.1056/NEJMoa040938
  4. Kim KS, Jeong JY, Kim YC, Na KJ, Park CS, Baek SM, et al. Predictors of response to gefitinib in refractory non-small cell lung cancer. Clin Cancer Res 2005;11:2244-51 https://doi.org/10.1158/1078-0432.CCR-04-2081
  5. Kim HJ, Jeong MP, Heo DS, Bang YJ, Han SK, Shin YS, et al. Lung cancer in Korea (1980-1984). Korean J Med 1994;46:221-8
  6. Scientific Committee of Korean Academy of Tuberculosis and Respiratory Disease. The National Survey of Lung Cancer in Korea. Tuberc Respir Dis 1999;46:455-65 https://doi.org/10.4046/trd.1999.46.4.455
  7. Ryu JS, Lee HJ, Leem JH, Kim L, Lee KH, Cho JH, et al. Clinical characteristics of primary lung cancer patients in a Tertiary Hospital. Tuberc Respir Dis 2006;60:321-9 https://doi.org/10.4046/trd.2006.60.3.321
  8. Munden RF, Swisher SS, Stevens CW, Stewart DJ. Imaging of the patient with non-small cell lung cancer. Radiology 2005;237:803-18 https://doi.org/10.1148/radiol.2373040966
  9. Jackman DM, Johnson BE. Small-cell lung cancer. Lancet 2005;366:1385-96 https://doi.org/10.1016/S0140-6736(05)67569-1
  10. Erasmus JJ, Truong MT, Munden RF. CT, MR, and PET imaging in staging of non-small-cell lung cancer. Semin Roentgenol 2005;40:126-42 https://doi.org/10.1053/j.ro.2005.01.004
  11. Kawamukai K, Cesario A, Margaritora S, Meacci E, Piraino A, Vita ML, et al. TNM independent prognostic factors in lung cancer. Rays 2004;29:373-6
  12. Kawamukai K, Cesario A, Margaritora S, Meacci E, Piraino A, Vita ML, et al. TNM independent prognostic factors in lung cancer. Rays 2004;29:373-6
  13. Alberg AJ, Samet JM. Epidemiology of lung cancer. Chest 2003;123:21S-49S https://doi.org/10.1378/chest.123.1_suppl.21S
  14. Patel JD, Bach PB, Kris MG. Lung cancer in US women: a contemporary epidemic. JAMA 2004;291: 1763-8.-7 https://doi.org/10.1001/jama.291.14.1763
  15. Janssen-Heijnen ML. Coebergh JW. The changing epidemiology of lung cancer in Europe. Lung Cancer 2003;41:245-58 https://doi.org/10.1016/S0169-5002(03)00230-7
  16. Osann KE. Epidemiology of lung cancer. Curr Opin Pulm Med 1998;4:198-204 https://doi.org/10.1097/00063198-199807000-00002