Numerous Bilateral Radiographically Dense Branching Opacities after Vertebroplasty with Polymethylmethacrylate

Polymethylmethacrylate를 이용한 경피적 척추성형술 후 흉부 X선에서 관찰된 다수의 양측성, 분지상 선상 음영

  • Cho, Jun Hyun (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Jung, Jong Pil (Department of Thoracic and Cardiovascular Surgery, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Eum, Jun-Bum (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Seo, Kwang Won (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Jegal, Yang Jin (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Choi, Seong Hoon (Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine) ;
  • Ahn, Jong Joon (Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine)
  • 조준현 (울산대학교 의과대학 울산대학교병원 내과) ;
  • 정종필 (울산대학교 의과대학 울산대학교병원 흉부외과) ;
  • 음준범 (울산대학교 의과대학 울산대학교병원 내과) ;
  • 서광원 (울산대학교 의과대학 울산대학교병원 내과) ;
  • 제갈양진 (울산대학교 의과대학 울산대학교병원 내과) ;
  • 최성훈 (울산대학교 의과대학 울산대학교병원 영상의학과) ;
  • 안종준 (울산대학교 의과대학 울산대학교병원 내과)
  • Received : 2006.06.27
  • Accepted : 2006.07.20
  • Published : 2006.08.30

Abstract

Percutaneous vertebroplasty consists of the percutaneous injection of polymethylmethacrylate (PMMA) cement into a collapsed vertebral body in order to obtain pain relief and mechanically strengthen the vertebral body. This procedure is now extensively used in treating osteoporotic vertebral compression fracture. It is an efficient treatment, but it is not free of complications. Most complications after vertebroplasty are associated with PMMA leakage. Pulmonary embolism of PMMA is rare, but this can occur when there is a failure to recognize venous migration of cement early during the procedure. We encountered a case of a patient with asymptomatic pulmonary embolism because of PMMA after percutaneous vertebroplasty. Chest X-ray and CT scanning revealed numerous tubular branching opacities that corresponded to the pulmonary vessels at the segmental and subsegmental levels.

경피적 척추성형술은 PMMA를 붕괴된 척추체에 경피적으로 주사하여 통증을 완화시키고 척추체를 구조적으로 보강하는 시술이다. 척추성형술은 아주 효과적인 치료방법이기는 하나 합병증이 전혀 없지는 않다. 척추성형술의 많은 합병증은 주로 PMMA 누출과 관련되어 있다. 대부분의 누출은 증상이 없고 또한 폐색전증은 매우 드물지만 시술도중 PMMA의 혈관내 이동을 조기에 발견하지 못할 때 발생할 수 있다. 저자들은 천식으로 인한 기침으로 내원한 환자의 흉부X선에서 우연히 PMMA에 의한 폐색전증을 진단하였기에 문헌 고찰과 함께 보고하는 바이다.

Keywords

References

  1. Verlaan JJ, Oner FC, Dhert WJ. Anterior spinal column augmentation with injectable bone cements. Biomaterials 2006;27:290-301 https://doi.org/10.1016/j.biomaterials.2005.07.028
  2. Laredo JD, Hamze B. Complications of percutaneous vertebroplasty and their prevention. Skeletal Radiol 2004;33:493-505
  3. Padovani B, Kasriel O, Brunner P, Peretti-Viton P. Pulmonary embolism caused by acrylic cement: a rare complication of percutaneous vertebroplasty. Am J Neuroradiol 1999;20:375-7
  4. Amar AP, Larsen DW, Esnaashari N, Albuquerque FC, Lavine SD, Teitelbaum GP. Percutaneous transpedicular polymethylmethacrylate vertebroplasty for the treatment of spinal compression fractures. Neurosurgery 2001;49:1105-14 https://doi.org/10.1097/00006123-200111000-00017
  5. Choe DH, Marom EM, Ahrar K, Truong MT, Madewell JE. Pulmonary embolism of polymethyl methacrylate during percutaneous vertebroplasty and kyphoplasty. AJR Am J Roentgenol 2004;183:1097- 102 https://doi.org/10.2214/ajr.183.4.1831097
  6. Barragan-Campos HM, Vallee JN, Lo D, Cormier E, Jean B, Rose M, et al. Percutaneous vertebroplasty for spinal metastases: complications. Radiology 2006; 238:354-62 https://doi.org/10.1148/radiol.2381040841
  7. Seo JS, Kim YJ, Choi BW, Kim TH, Choe KO. MDCT of pulmonary embolism after percutaneous vertebroplasty. AJR Am J Roentgenol 2005;184:1364-5 https://doi.org/10.2214/ajr.184.4.01841364
  8. Yoo KY, Jeong SW, Yoon W, Lee J. Acute respiratory distress syndrome associated with pulmonary cement embolism following percutaneous vertebroplasty with polymethylmethacrylate. Spine 2004;29:E294-7 https://doi.org/10.1097/01.BRS.0000131211.87594.B0
  9. Jung KW, Ko YH, Kim HC,Wi JS, Moon JM, Chun BJ, et al. A case of fatal pulmonary embolism caused by bone cement after percutaneous vertebroplasty. J Korean Soc Emerg Med 2003;14:121-4
  10. Choi Y, Han HC, Lim KJ. Pulmonary embolism after percutaneous vertebroplasty with polymethymethacrylate. J Korean Pain Soc 2002;15:190-3
  11. Jang JS, Lee SH, Jung SK. Pulmonary embolism of polymethylmethacrylate after percutaneous vertebroplasty: a report of three cases. Spine 2002;27:E416-8 https://doi.org/10.1097/00007632-200210010-00021
  12. Park CB, Yi MZ, Kim SD, Joo SJ, Yeo YS, Hong MK, et al. Acute pericarditis caused by penetrated polymethylmethacrylate of the right ventricle after percutaneous vertebroplasty. Korean J Med 2004;67:528-31