Tuberculosis and Respiratory Diseases

  • 제61권2호
  • /
  • Pages.171-177
  • /
  • 2006
  • /
  • 1738-3536(pISSN)
  • /
  • 2005-6184(eISSN)
대한결핵및호흡기학회 (The Korean Academy of Tuberculosis and Respiratory Diseases)
권호 표지

고립성 폐결절로 발현한 파종성 림프절 외 변연부 B-세포 림프종 1예

A Case Report of Disseminated Extranodal Marginal Zone B-Cell Lymphoma of MALT Manifested by Solitary Pulmonary Nodule

  • 조준현 (울산대학교병원 내과) ;
  • 정종필 (울산대학교병원 흉부외과) ;
  • 차희정 (울산대학교병원 병리과) ;
  • 박창률 (울산대학교병원 흉부외과) ;
  • 김성률 (울산대학교병원 진단검사의학과) ;
  • 김혁 (울산대학교병원 내과) ;
  • 박진우 (울산대학교병원 내과) ;
  • 우순주 (울산대학교병원 내과) ;
  • 엄은아 (울산대학교병원 내과) ;
  • 이기영 (울산대학교병원 내과) ;
  • 제갈양진 (울산대학교병원 내과)
  • Cho, Joon Hyun (Department of Internal Medicine, Ulsan University Hospital) ;
  • Jung, Jong Pil (Department of Thoracic and Cardiovascular Surgery, Ulsan University Hospital) ;
  • Cha, Hee Jeong (Department of Pathology, Ulsan University Hospital) ;
  • Park, Chang Ryul (Department of Thoracic and Cardiovascular Surgery, Ulsan University Hospital) ;
  • Kim, Sung Ryul (Department of Laboratory Medicine. Ulsan University Hospital) ;
  • Kim, Hawk (Department of Internal Medicine, Ulsan University Hospital) ;
  • Park, Jin Woo (Department of Internal Medicine, Ulsan University Hospital) ;
  • Woo, Soon Joo (Department of Internal Medicine, Ulsan University Hospital) ;
  • Eum, Eun A (Department of Internal Medicine, Ulsan University Hospital) ;
  • Lee, Ki Young (Department of Internal Medicine, Ulsan University Hospital) ;
  • Jegal, Yang Jin (Department of Internal Medicine, Ulsan University Hospital)
  • 투고 : 2006.04.18
  • 심사 : 2006.06.23
  • 발행 : 2006.08.30
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초록

MALT림프종은 질병의 진행이 느리고, 진단 당시 국소적인 병변이 대부분이며, 폐와 위장관을 동시에 침범하는 경우는 매우 드물다. 저자들은 흉부 단순촬영에서 고립성 폐결절이 발견된 73세 남자 환자에서 위, 폐, 골수를 침범한 파종성 MALT림프종 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) is usually indolent. Although it was reported recently that about 20-30% cases of MALT lymphoma presented with a disseminated disease at diagnosis, it was described as a disease localized at diagnosis and remaining stable for a prolonged period. However, only a few cases of MALT lymphoma involved the lung and gastrointestinal tract all at once. We report a case of a 73-year-old man with disseminated MALT lymphoma. He presented with non-productive cough, initial chest radiograph showed a nodule in the right lower lobe. The diagnosis of stage IV MALT lymphoma was made by CT scan, video-assisted thoracoscopic excisional biopy, gastrofiberscopic biopsy and bone marrow biopsy. The lymphoma involved the lung, stomach and bone marrow at the time of diagnosis. Because he refused chemotherapy, he discharged after Helicobacter pylori eradication without chemotherapy. Regular follow-up examination did not show any evidence of disease progression over 22 months.

키워드

참고문헌

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