Pediatric Gastroenterology, Hepatology & Nutrition

The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition (대한소아소화기영양학회)
권호 표지

A Case of PFAPA Syndrome Mimicking Cyclic Vomiting Syndrome

주기성 구토증으로 추적 관찰 중 진단된 PFAPA 증후군 1예

  • Hong, Seok Pyo (Department of Pediatrics, Keimyung University School of Medicine) ;
  • Shin, Hyun Jung (Department of Pediatrics, Keimyung University School of Medicine) ;
  • Kim, Yeo Hyang (Department of Pediatrics, Keimyung University School of Medicine) ;
  • Choe, Byung Kyu (Department of Pediatrics, Keimyung University School of Medicine) ;
  • Choi, Won Jung (Hyosung Children's Hospital) ;
  • Kim, Ae Suk (Department of Pediatrics, Dongguk University College of Medicine) ;
  • Hwang, Jin-Bok (Department of Pediatrics, Keimyung University School of Medicine)
  • 홍석표 (계명대학교 의과대학 소아과학교실) ;
  • 신현정 (계명대학교 의과대학 소아과학교실) ;
  • 김여향 (계명대학교 의과대학 소아과학교실) ;
  • 최병규 (계명대학교 의과대학 소아과학교실) ;
  • 최원정 (효성아동병원) ;
  • 김애숙 (동국대학교 의과대학 소아과학교실) ;
  • 황진복 (계명대학교 의과대학 소아과학교실)
  • Received : 2006.01.31
  • Accepted : 2006.02.22
  • Published : 2006.03.01
Download PDF
⟨ Previous Next ⟩

Abstract

PFAPA syndrome is characterized by periodic fevers associated with aphthous stomatitis, pharyngitis, and cervical adenitis and is unusual in infants and children. We report on a case of PFAPA syndrome mimicking cyclic vomiting syndrome in a 42-month-old girl. She had experienced multiple episodes of cyclic vomiting with abdominal pain from age 20 to 30 months. When she was 30 months old, periodic fever with pharyngitis was combined with cyclic vomiting, and when 40 months old, aphthous stomatitis and cervical adenitis were added. These periodic symptoms and signs were not treated with prokinetics or antibiotics. Symptom duration of an episode was 3 days. After cimetidine therapy (150 mg three times daily for 6 months), her febrile and cyclic vomiting episodes ceased. At the time of writing she had not received therapy for 10 months and has remained well without periodic attack.

주기성 구토증의 심하에 추적 관찰 중 주기적인 발열, 아프타성 구내염, 인두염 및 경부 림프절염 등의 특징적인 임상증상을 보여 소아에서 주기적 발열을 일으키는 원인들을 증상과 검사실 소견을 통 해 배제함으로써 PFAPA 증후군으로 진단된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords