References
- Tao SH, Bolger PM. 1997. Hazard assessment of germanium supplements. Regul Toxicol Pharmacol 25: 211-219 https://doi.org/10.1006/rtph.1997.1098
- Schauss AG. 1991. Nephrotoxicity and neurotoxicity in human from organogermanium compounds and germa-nium dioxide. Biol Trace Elem Res 29: 267-280 https://doi.org/10.1007/BF03032683
- Suzuki F, Brutkiewicz RR, Pollard RB. 1985. Importance of T-cells and macrophages in the antitumor activity of carboxyethylgermanium sesquioxide (Ge-132). Anticancer Res 5: 479-483
- Aso H, Suzuki F, Yamaguchi T, Hayashi Y, Ebina T, Ashida N. 1985. Induction of interferon and activation of NK cells and macrophages in mice by oral adminis-tration of Ge-132, and organic germanium compound. Microbiol Immunol 29: 65-74 https://doi.org/10.1111/j.1348-0421.1985.tb00803.x
- Hammett FS, Nowrey JE Jr, Muller JH. 1992. The erythro-poi-etic action of germanium dioxide. J Exp Med 35: 173-180 https://doi.org/10.1084/jem.35.2.173
- Nakada Y, Kosaka T, Kuwabara M, Tanaka S, Sato K, Koide F. 1993. Effects of 2-carboxyethylgermanium sesquioxide (Ge-132) as an immunological modifier of postsurgical immunosuppression in dogs. J Vet Med Sci 55: 795-799 https://doi.org/10.1292/jvms.55.795
- Sijpesteijn AK, Rukens F, Van Der Kerk GJ, Manten A. 1964. Antimicrobial activity of organogermanium derivatives. Nature 201: 736
- Han C, Yin WG, Shen M. 1992. Inhibition by ger-manium oxide of the mutagenicity of cadmium chloride in various genotoxicity assays. Food Chem Toxicol 30: 521-524 https://doi.org/10.1016/0278-6915(92)90104-S
- Lee CH, Lin RH, Liu SH, Lin-Shiau SY. 1998. Effects of germanium oxide and other chemical compounds on phenylmercury acetate-induced genotoxicity in cultured human lymphocytes. Environ Mol Mutagen 31: 157-162 https://doi.org/10.1002/(SICI)1098-2280(1998)31:2<157::AID-EM7>3.0.CO;2-J
- Sanai T, Okuda S, Onoyama K, Oochi N, Takaichi S, Mizuhira V, Fujishima M. 1991a. Chronic tubulointerstitial changes induced by germanium dioxide in comparison with carboxyethylgermanium sesquioxide. Kidney Int 40: 882-890 https://doi.org/10.1038/ki.1991.289
- Sanai T, Onoyama K, Osato S, Motomura K, Oochi N, Oh Y, Okuda S, Takaichi S, Fujishima M. 1991b. Dose dependency of germanium dioxide-induced nephrotoxicity in rats. Nephron 57: 349-354 https://doi.org/10.1159/000186286
- Wei XS. 1992. Effect of yeast on bioenrichment of germanium. Food Science 149: 49-54
- Klapcinska B, Chmielowski J. 1986. Binding of germa-nium to Pseudomonas putida cells. Appl Environ Microbiol 51: 1144-1147
- Lynn MR, Geoffrey MG. 1997. Mutants of Sacchromyces cerevisiae defective in vacuolar function a role for the vacuole in toxic metal ion detoxification. Microbiol Lett 152: 293-298 https://doi.org/10.1111/j.1574-6968.1997.tb10442.x
- Van Dyke MI, Lee H, Travors JT. 1989. Ger-manium toxicity in selected bacterial and yeast stains. J Ind Microbiol 4: 299-306 https://doi.org/10.1007/BF01577353
- Song WJ, Lee SC, Oh TK. 1995. Preparation of organic germanium by yeast cell. Kor J Appl Microbiol Biotechnol 23: 87-90
- Lee SH, Ahn SD, Rho SN, Sohn TU. 2005. A study on preparation and binding properties of germanium-fortified yeast. J Korean Soc Appl Biol Chem 48: 382-387
-
Lee JS, Park JI, Kim SH, Park SH, Kang SK, Park CB, Sohn TU, Jang JY, Kang JK, Kim YB. 2004. Oral single and repeated-dose toxicity studies on Geranti Bio-Ge
$Yeast^{\circledR}$ , organic germanium fortified yeasts, in rats. J Toxicol Sci 29: 541-553 https://doi.org/10.2131/jts.29.541 - Sanai T, Oochi N, Okuda S, Osato S, Kiyama S, Komota T, Onoyama K, Fujishima M. 1990. Sub-acute nephrotoxicity of germanium dioxide in the exper-imental animal. Toxicol Appl Pharmacol 103: 345-354 https://doi.org/10.1016/0041-008X(90)90234-L
- Lee JS, Park JI, Kim SH, Park SH, Lee HY, Hwang ZZ, Park, CB, Sohn TU, Shin SH, Kang JK, Kim YB. 2004. Oral single and repeated-dose toxicity studies on Geranti Bio-Ge yeast, organic germanium-fortified yeasts, in dogs. J Toxicol Sci 29: 555-569 https://doi.org/10.2131/jts.29.555
- Min SJ, Zheng MS, Park JI, Lee JS, Kim YB, Kang JK, Sohn TU, Park CB. 2004. Genotoxicity studies on Geranti Bio-Ge Yeast, an organic germanium synthesized in yeasts. Korean J Lab Ani Sci 20: 81-88
- Matsusaka T, Fujii M, Nakano T, Terai T, Kurata A, Imaizumi M, Abe H. 1988. Germanium-induced neophro-pathy: report of two cases and review of the literature. Clinical Nephrology 30: 341-345
- Okada K, Okagawa K, Kawakami K, Kuroda Y, Morizumi K, Sato H, Morita H, Shimomura S, Saito S. 1989. Renal failure caused by long-term use of a germanium preparation as an elixir. Clinical Nephrology 31: 219-224
- Ahn DC, Choi YS, Park DH, Park SY, Han ZZ, Song IS, Kim EJ, Lee MS, Kwon MS. 2001. Chronic toxicity of dry yeast-G (biogermanium) orally administered to rats for consecutive months. Korean J Lab Anin Sci 17: 109-118
- Schroeder HA, Balassa JJ. 1967. Arsenic, ger-manium, tin, and vanadium in mice. Effects on growth, survical and tissue levels. J Nutr 92: 245-252 https://doi.org/10.1093/jn/92.2.245
- Chen Y, Wang N, Shangguan G, Chen Y. 1993. Deter-mination of germanium in urine an syudies on pharma-cokinetics of Ge-132 in body. Zhongguo Yiyuan Yaoxue Zazhi 13: 103-105
- Miyao K, Onishi T, Asai K, Tomizawa S, Suzuki F. 1980. Toxicology and phase I studies on a novel organogermanium compound, Ge-132. Curr Chemother Infect Dis 2: 1527- 1529
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