대한한방소아과학회지 (The Journal of Pediatrics of Korean Medicine)

  • 제20권3호
  • /
  • Pages.129-141
  • /
  • 2006
  • /
  • 1226-8038(pISSN)
  • /
  • 2287-9463(eISSN)
대한한방소아과학회 (The Association of Korean Oriental Pediatrics)
권호 표지

한약의 아토피 피부염 치료에 대한 예비 임상 연구

A Pilot Study of Herb Medication for Atopic Dermatitis

  • 임영권 (수원 함소아한의원) ;
  • 정지아 (수원 함소아한의원) ;
  • 윤철상 (수원 함소아한의원) ;
  • 허광욱 (수원 함소아한의원) ;
  • 이훈 (구리 함소아한의원) ;
  • 김호철 (경희대학교 한의과대학 본초학교실) ;
  • 김영란 (경희대학교 동서의학대학원 의학영양학과) ;
  • 조윤희 (경희대학교 동서의학대학원 의학영양학과)
  • Lim, Young-Kwon (Suwon Hamsoa oriental clinic) ;
  • Jung, Ji-A (Suwon Hamsoa oriental clinic) ;
  • Yun, Cheol-Sang (Suwon Hamsoa oriental clinic) ;
  • Hur, Kwang-Wook (Suwon Hamsoa oriental clinic) ;
  • Lee, Hun (Guri Hamsoa oriental clinic) ;
  • Kim, Ho-Chyul (Dept. of Herbology, Kyung Hee University) ;
  • Kim, Young-Ran (Dept. of Medical Nutrition, Kyung Hee University, Graduate School of East-West Medical Science) ;
  • Cho, Yun-Hi (Dept. of Medical Nutrition, Kyung Hee University, Graduate School of East-West Medical Science)
  • 발행 : 2006.12.31
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objectives : The purpose of this study is to determine clinical efficacy of herbal medicine by evaluating SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis Methods : Subjects are divided into two groups : Group 1(non-differentiation children treated with Saenghyeoryunbueom) and group 2(differentiation children treated with either pyungwisan, onchungum or gamitongsungsan). We determine SCORAD Index and total level of ceramaides in the skin of 13 children with atopic dermatitis before and after taking each of herbal treatment for 12 weeks. Results : After herbal prescription for 12 weeks, A SCORAD index of both group 1 and group 2 was decreased. However, the total level of ceramides in group 1 and group 2 was not altered after 12 weeks. When the correlation between the alteration of SCORAD index and ceramides levels was determined, the SCORAD index in group 1 was inversely correlated with the total level of ceramides(r=-0.994, p=0.006) In contrast, the alteration of SCORAD index in group 2 was not correlated with ceramide levels. Conclusions : The clinical efficacy of Saenghyeoryunbueom for non-differentiation children with atopic dermatitis is paralleled with the increased level of ceramides in skin. The clinical efficacy of pyungwisan, onchungum or gamitongsungsan for differentiation children with atopic dermatitis is not correlated with ceramide level in skin.

키워드