Journal of Acupuncture Research

Korean Acupuncture & Moxibustion Medicine Society (대한침구의학회)
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Effects of Low Frequency Electro-Acupuncture (ST36) on the Adjuvant-Induced Arthritis in Rats

저빈도(低頻度) 족삼리(足三里) 전함랄극(電緘剌戟)이 흰쥐의 Adjuvant 유발(誘發) 관절염(關節炎)에 미치는 영향(影響)

  • Kim, Jong-Chul (Department of Meridian & Acupoint, College of Oriental Medicine, Se Myung University) ;
  • Lee, Eun-Yong (Department of Acupuncture & Moxibustion, College of Oriental Medicine, Se Myung University) ;
  • Seo, Il-Beok (Department of Anatomy, College of Oriental Medicine, Se Myung University) ;
  • Koo, Sung-Tae (Department of Medical Research, Korea Institute of Oriental Medicine) ;
  • Choi, Sung-Mi (Department of Medical Research, Korea Institute of Oriental Medicine) ;
  • Kim, Ee-Hwa (Department of Meridian & Acupoint, College of Oriental Medicine, Se Myung University)
  • 김종철 (세명대학교 한의과대학 경락 경혈학교실) ;
  • 이은용 (세명대학교 한의과대학 침구학교실) ;
  • 서일복 (세명대학교 한의과대학 해부학교실) ;
  • 구성태 (한국한의학연구원 의료연구부) ;
  • 최선미 (한국한의학연구원 의료연구부) ;
  • 김이화 (세명대학교 한의과대학 경락 경혈학교실)
  • Published : 2006.12.20
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Abstract

Objectives : This study was to investigate the effect of low frequency electro-acupuncture (EA) at ST36 acupoint on the Freund's Complete Adjuvant(FCA)-induced arthritis in rats. Methods : Arthritis was induced by intradermal injection of FCA into base of tail. Experimental groups were divided into 4 groups; Normal, Control, ST36 and Non-Acupoint(NA). ST36 group was treated by 2 Hz EA at ST36 acupoint. Body weight, paw edema volun1e and ankle joint thickness were measured after treatment. And we investigated the effects of 2 Hz EA via WBC count, segment neurophil, lymphocyte, PGE2 assay and NADPH-d histochemistry. Results and Conclusion : The mean of body weight and ankle joint thickness of ST36 group was increased compared with control group. The mean of paw edema volume, WBC count, segment neutrophil and lymphocyte of were not decreased with control group. The mean of PGE2 concentration and NADPH-d positive neurons were changed significantly compared with control group.

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