대한임상검사과학회지 (Korean Journal of Clinical Laboratory Science)

  • 제38권1호
  • /
  • Pages.59-64
  • /
  • 2006
  • /
  • 1738-3544(pISSN)
  • /
  • 2288-1662(eISSN)
대한임상검사과학회 (Korean Society for Clinical Laboratory Science)
권호 표지

Tribenzylamine Ionophore를 이용한 pH-ISE의 제조 및 임상응용

Preparation and Clinical Application of pH-ISE(Ion Selective Electrode) Based on Tribenzylamine Ionophore

  • 조동회 (서울산업대학교 화학공학과) ;
  • 박정오 (서울보건대학 임상병리과)
  • Cho, Dong-Hoe (Department of Chemical Engineering, Seoul National University of Technology) ;
  • Park, Chung-Oh (Department of Biomedical Laboratory Science, Seoul Health College)
  • 발행 : 2006.04.30
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초록

The pH-ISE(ion selective electrode) based on tribenzylamine as a hydrogen ion carrier was prepared and its electrochemical characterization was studied. It responded linearly to hydrogen ions in the range of pH 3.1 - pH 11.0 and the Nernstian slope showed 55.0 mV/pH (at $20{\pm}0.2^{\circ}C$), it also showed a fast response time of 8 sec. When it was directly applied to human blood(pH 6.0-8.5), we could get the same satisfying results. A good reproducibility and stability were shown with the precision of 2 mV (${\pm}0.1$). The pH-ISE based on tribenzylamine exhibited biocompatibility in clinical applications.

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