Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)
- Volume 38 Issue 1
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- Pages.9-15
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- 2006
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- 1738-3544(pISSN)
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- 2288-1662(eISSN)
A Study of Peripheral Blood Stem Cell Collection and Bone Marrow Engraftment after Peripheral Blood Stem Cell Transplantation
말초혈액 조혈모세포 채혈 및 이식 후 생착에 관한 연구
- Son, Gye-Sung (Department of Clinical Laboratory Science, Eulji University) ;
- Kwon, Heung-Man (Department of Laboratory Medicine, Chungnam University Hospital) ;
- Kwon, Gye-Cheol (College of Medicine, Chungnam National University)
- Published : 2006.04.30
Abstract
Peripheral bood stem cell collection (PBSCC), including peripheral blood stem cell transplantation (PBSCT), has been utilized worldwide as a very beneficial treatment method instead of allogenic Bone Marrow Transplantation (BMT) because it has many advantages such as rapid bone marrow engraftment and hematopoietic recovery, easy and safe accessibility and lower risk of rejection compared with allogenic BMT. In order to identify most the observable parameter in PBSCC, we analyzed various hematological parameters before and after PBSCC, and evaluated the correlation between the time of bone marrow engraftment and the number of CD34+ cells. Thirteen patients, who underwent 54 PBSCCs from January, 2003 to August, 2004 at Chungnam National University Hospital due to various systemic neoplasms, were analyzed in aspects of various hematological parameters including CD34+ cells using by Flow Cytometry (FCM). PBSCC harvests are described below: Mononuclear cells (MNC)
Keywords
- Peripheral Blood Stem Cell Collection(PBSCC);
- Peripheral Blood Stem Cell Transplantation(PBSCT);
- Bone Marrow Tranplantation(BMT);
- Mononuclear Cell(MNC);
- Absolute Neutrophile Count(ANC)