Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
권호 표지

The change of oral volatile sulfur compounds(VSC) concentration after periodontal treatment

치주치료 후 구강 내 Volatile Sulfur Compounds(VSC)의 변화

  • Kim, Sung-Hyun (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration, National Health Insurance Corporation Ilsan Hospital) ;
  • Chae, Gyeong-Jun (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Jung, Ui-Won (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Kim, Chang-Sung (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Choi, Seong-Ho (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Cho, Kyoo-Sung (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Chai, Jung-Kyu (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Kim, Chong-Kwan (Department of Periodontology, College of Dentistry, Yonsei University, Reasearch Institute for Periodontal Regeneration) ;
  • Bang, Eun-Gyeong (National Health Insurance Corporation Ilsan Hospital)
  • 김성현 (연세대학교 치주과학교실, 치주조직 재생 연구소, 국민건강보험공단 일산병원) ;
  • 채경준 (연세대학교 치주과학교실, 치주조직 재생 연구소) ;
  • 정의원 (연세대학교 치주과학교실, 치주조직 재생 연구소) ;
  • 김창성 (연세대학교 치주과학교실, 치주조직 재생 연구소) ;
  • 최성호 (연세대학교 치주과학교실, 치주조직 재생 연구소) ;
  • 조규성 (연세대학교 치주과학교실, 치주조직 재생 연구소) ;
  • 채중규 (연세대학교 치주과학교실, 치주조직 재생 연구소) ;
  • 김종관 (연세대학교 치주과학교실, 치주조직 재생 연구소) ;
  • 방은경 (국민건강보험공단 일산병원)
  • Published : 2006.09.30
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Abstract

Oral malodor may cause a significant social or psychological handicap to those suffering from it. Oral malodor has been correlated with the concentration of volatile sulfur compounds (VSC) produced in the oral cavity. Specific bacteria identified in the production of VSC have been reported and many of these bacteria are commonly suspected periodontal pathogens. The aim of this study was to estimate the change of the VSC concentration after periodontal treatment, Twenty subjects with probing depth $(PD)\;{\geq}5mm$ (experimental group) and 20 subjects with PD<5mm (control group) participated. VSC concentration measurement was made with gas chromatography. VSC concentration was measured at pre-treatment, 2 weeks after scaling and 1 month after periodontal treatment(root planning and flap operation). Maximum probing depth and bleeding on probing(BOP) were also examed at pretreatment and 1 month after periodontal treatment, The conclusions were as follow: 1. In the experimental group VSC concentration and CH3SH/H2S ratio were higher than control group. (p<0.05) 2. Both VSC concentration and CH3SH/H2S ratio showed decrease after periodontal treatment, But only CH3SH/H2S ratio after 1 month periodontal treatment was statistically significantly different from pre-treatment. (p<0.05) 3. CH3SH/H2S ratio tended to be on increase according to maximum probing depth and bleeding on probing. Periodontal disease could be a factor that caused oral malodor and oral malodor could be decreased after periodontal treatment.

Keywords

References

  1. 이재명, 임성빈, 정진형, 홍기석. 치주질환 후 구취감소에 대한 연구. 대한치주과학회지, 2004; 34(2):449-459
  2. Awano S, Gohara K, Kurihara E, Ansai T, Takehara T, The relationship between the presence of periodontopathogenic in saliva and halitosis. Int Dent J 2002;52 suppl 3:212-216 https://doi.org/10.1002/j.1875-595X.2002.tb00927.x
  3. Coil JM, Tonzetich J. Characterization of volatile sulphur compound production at individual gingival crevicular sites in humans. J Clin Dent 1992;3:97-103
  4. Delanghe G, Ghyselen J, van Steenberghe D. Feenstra L, Multidisciplinary breath -odor clinic. Lancet 1997;350;187
  5. Figueiredo LC, Rosetti EP, Marcantonio E Jr, Marcantonio RA, Salvador SL, The relationship of oral malodor in patients with or without periodontal disease. J Periodontol 2002 ;73:1338-1342 https://doi.org/10.1902/jop.2002.73.11.1338
  6. Johnson PW, Yaekaki, Tonzetich J, Effect of volatile thiol compounds on protein metabolism by human gingival fibroblasts. J Periodontal Res 1992;27:553-561 https://doi.org/10.1111/j.1600-0765.1992.tb01736.x
  7. Johnson PW, Yaekaki K, Tonzetich J. Effect of methyl mercaptan on synthesis and degradation of collagen. J Periodontal Res 1996;31:323-329 https://doi.org/10.1111/j.1600-0765.1996.tb00499.x
  8. Kaizu T. Analysis of volatile sulphur conpounds in mouth air by gas chromatography. J Japan Ass Periodont 1976;18:1-12 https://doi.org/10.2329/perio.18.1
  9. Mrita M, Hom-Lay Wang. Relationship between sulcular sulfide level and oral malodor in subjects with periodontal disease. J Periodontol 2001;72:79-84 https://doi.org/10.1902/jop.2001.72.1.79
  10. Morita M, Wang H-L. Association between oral malodor and adult periodontitis. a review. J Clin Periodontol 2001;28:813-819 https://doi.org/10.1034/j.1600-051x.2001.028009813.x
  11. Ng W. & Tonzetich J. Effect of hydrogen sulfide and methyl mercaptan on the permeability of oral mucosa. J Dent Res 1984; 63:994-997 https://doi.org/10.1177/00220345840630071701
  12. Oxtoby A. & Field EA. Delusional symptoms in dental patients: a report of four cases. Br Dent J 1994;176:140-142 https://doi.org/10.1038/sj.bdj.4808390
  13. Persson S, Edlund ME, Claesson R, Carlsson J. The formation of hydrogen sulfide and methyl mercaptan by oral bacteria. Oral Microbiol Imrnunol 1990;5:195-201 https://doi.org/10.1111/j.1399-302X.1990.tb00645.x
  14. Persson S. Volatile sulfur compounds in periodontal pockets (Dissertation). Umea, Sweden. Umea University 1993;64
  15. Ratcliff P.A. Johnson P. W. The relationship between oral malodor, gingivitis and periodontitis, A review. J Periodontol 1999;70: 485-489 https://doi.org/10.1902/jop.1999.70.5.485
  16. Ratkay LG, Waterfield JD, Tonzetich J. Stimulation of enzyme and cytokine production by methyl mercaptan in human gingival fibroblast and monocyte cell cultures. Arch Oral BioI 1995;40:337-344 https://doi.org/10.1016/0003-9969(94)00165-8
  17. Rosenberg M, Kulkarni GV, Bosy A. McCulloch CAG. Reproducibility and sensitivity of oral malodor measurements with a portable sulfide monitor. J Dent Res 1991;70:1436-1440 https://doi.org/10.1177/00220345910700110801
  18. Rosenberg M. Clinical assessment of bad breath: Current concepts. J Am dent Assoc 1996;127:475-482 https://doi.org/10.14219/jada.archive.1996.0239
  19. Tonzethich J. Production and origin of oral malodor. a review of mechanism and method of analysis. J Peiodontol 1977;48:13-20 https://doi.org/10.1902/jop.1977.48.1.13
  20. Tonzetich J. Oral malodour, An indicator of health status and oral cleanliness. Int Dent J 1978;28:309-319
  21. Yaegaki K, SanadaK, Volatile sulfur compounds in mouth air from clinically healthy subjects and patients with periodontal disease. J Periodontal Res 1992;27:233-238 https://doi.org/10.1111/j.1600-0765.1992.tb01673.x
  22. Zhu W, Sha Y. The relationship between oral malodor, VSCs levels in the mouth air with periodontitis and tongue coating. Zhonghua Kou Qiang Yi Xue Za Zhi 2002;37: 300-303