Plasma Choline Concentration of Some Korean Young Adults and Correlation with Dietary Choline Intake

젊은 성인의 혈장 콜린 농도와 콜린 섭취량과의 상관성

  • Na Jin-Seok (Department of Food and Nutrition, Chungnam National University) ;
  • Cho Hyo-Jung (Department of Food and Nutrition, Chungnam National University) ;
  • Lim Jong-Hwan (Department of College of Veterinary Medicine, Chungnam National University) ;
  • Yun Hyo-In (Department of College of Veterinary Medicine, Chungnam National University) ;
  • Sok Dai-Eun (Department of College of Pharmacy, Chungnam National University) ;
  • Lee Ju-Woon (Radiation Food Science and Biotechnology Team, Korea Atomic Energy Research Institute) ;
  • Byun Myung-Woo (Radiation Food Science and Biotechnology Team, Korea Atomic Energy Research Institute) ;
  • Chung Young-Jin (Department of Food and Nutrition, Chungnam National University)
  • 나진석 (충남대학교 생활과학대학 식품영양학과) ;
  • 조효정 (충남대학교 생활과학대학 식품영양학과) ;
  • 임종환 (충남대학교 수의과대학) ;
  • 윤효인 (충남대학교 수의과대학) ;
  • 석대은 (충남대학교 약학대학) ;
  • 이주운 (한국원자력연구소 방사선식품.생명공학연구팀) ;
  • 변명우 (한국원자력연구소 방사선식품.생명공학연구팀) ;
  • 정영진 (충남대학교 생활과학대학 식품영양학과)
  • Published : 2006.03.01

Abstract

The purpose of this study is to investigate the concentration of plasma choline of Korean and to clarify the relationship between plasma choline concentration and choline intake. Plasma choline concentration of 30 young adults (15 males, 15 females) aged 20-30 years living in Deajeon metropolitan city are analyzed and their dietary choline intake. Choline content of one day meal was directly analyzed with the use of enzymatic method. Plasma choline concentration from more than 12 hr fasting blood was analyzed by using HPLC-MS. Choline intakes of male subjects were in the range of 253.51-1724.14 mg and those of female subjects were in the range of 240.85-938.06 mg. Mean intakes of choline were $634.53{\pm}353.68mg$ in male subjects and $473.99{\pm}183.76mg$ in female subjects. Plasma choline concentration of total subjects was in the range of 5.08-14.01 ${\mu}mol/L$. Mean plasma choline concentration was $9.19{\pm}2.05{\mu}mol/L$ in male subjects and $8.11{\pm}1.70{\mu}mol/L$ in female subjects. Plasma choline concentration did not show significant correlation with choline intake in male and total subjects, but showed positive correlation with choline intake in female subjects (p<0.05). This result shows that more studies on large scaled samples are needed.

Keywords

References

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