Biomolecules & Therapeutics

The Korean Society of Applied Pharmacology (한국응용약물학회)
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Recent Advances in Anti-inflammatory Flavonoid Research since 2004

  • Kim Hyun-Pyo (College of Pharmacy, Kangwon National University)
  • Published : 2006.03.01
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Abstract

Certain flavonoids possess anti-inflammatory activity. Besides their antioxidative property, the cellular action mechanisms of flavonoids include an inhibition of arachidonate metabolizing enzymes such as cyclooxygenases and lipoxygenases, and a down-regulation of proinflammatory gene expression such as cyclooxygenase-2, inducible nitric oxide synthase and tumor necrosis factor-$\alpha$. In this review, the recent findings of anti-inflammatory flavonoid research since 2004 were summarized. And the cellular mechanisms on signal transduction pathways were also discussed.

Keywords

References

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