Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
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Flavones with Free Radical Scavenging Activity from Goniothalamus tenuifolius

  • Likhitwitayawuid Kittisak (Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University) ;
  • Klongsiriwet Chaweewan (Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University) ;
  • Jongbunprasert Vichien (Department of Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University) ;
  • Sritularak Boonchoo (Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University) ;
  • Wongseripipatana Samphan (Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University)
  • Published : 2006.03.01
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Abstract

From the leaves of Goniothalamus tenuifolius, a new natural product namely 3'-hydroxy-3,5,7,4'-tetramethoxyflavone (1) was isolated, along with seven other known compounds (2-8). Each of these isolates was evaluated for free radical scavenging activity on the DPPH decoloration test. The data obtained in this study suggested that the ortho 3',4'-diphenolic structure was essential for the activity of these flavonol derivatives.

Keywords

References

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