New Butyrylcholinesterase Inhibitory Triterpenes from Salvia santolinifolia

  • Mehmood Sajid (Pharmaceutical Research Centre, PCSIR Laboratories Complex) ;
  • Riaz Naheed (Pharmaceutical Research Centre, PCSIR Laboratories Complex) ;
  • Nawaz Sarfraz Ahmed (International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi) ;
  • Afza Nighat (Pharmaceutical Research Centre, PCSIR Laboratories Complex) ;
  • Malik Abdul (International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi) ;
  • Choudhary Muhammad Iqbal (International Centre for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi)
  • Published : 2006.03.01

Abstract

Slavins A (1) and B (2), the new amyrin type triterpenes, have been isolated from the chloroform soluble fraction of Salvia santolinifolia and assigned structures on the basis of spectral studies including 2D NMR. Both the compounds displayed inhibitory potential against the enzyme butyrylcholinesterase.

Keywords

References

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