Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Two Cases of Alopecia Totalis treated with Diphenylcyclopropenone (DPCP) Immunotherapy

Diphenylcyclopropenone (DPCP) 면역요법으로 호전된 전두 탈모증 2 예

  • Moon, Seok-Ki (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Shin, Young-Min (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Kim, Chan-Woo (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Shin, Dong-Hoon (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Choi, Jong-Soo (Department of Dermatology, College of Medicine, Yeungnam University) ;
  • Kim, Ki-Hong (Department of Dermatology, College of Medicine, Yeungnam University)
  • 문석기 (영남대학교 의과대학 피부과학교실) ;
  • 신영민 (영남대학교 의과대학 피부과학교실) ;
  • 김찬우 (영남대학교 의과대학 피부과학교실) ;
  • 신동훈 (영남대학교 의과대학 피부과학교실) ;
  • 최종수 (영남대학교 의과대학 피부과학교실) ;
  • 김기홍 (영남대학교 의과대학 피부과학교실)
  • Published : 2006.12.30
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Abstract

Treatments for alopecia areata include topical corticosteroid treatment, corticosteroid intralesional injection, systemic corticosteroid treatment, PUVA(psoralen-UVA) and topical immunotherapy. The therapeutic effects are variable. Alopecia totalis is hard to treat completely. Topical immunotherapy with dinitrochlorobenzene (DNCB), squaric acid dibutyl ester (SADBE) or diphenylcyclopropenone (diphencyprone, DPCP) represents the most accepted therapeutic modality for the treatment of extensive alopecia areata. We report two cases of alopecia totalis treated with DPCP. After DPCP treatment, total scalp hair was completely recovered.

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