대한한방부인과학회지 (The Journal of Korean Obstetrics and Gynecology)
- 제19권1호
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- Pages.125-138
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- 2006
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- 1229-4292(pISSN)
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- 2508-3619(eISSN)
도홍사물탕(桃紅四物湯)이 자궁내막증(子宮內膜症)을 유발한 흰쥐에 미치는 영향(影響)
Effects of Dohongsamul-tang on Surgically Induced Endometriosis in Rats
- Lim, Eun-Mee (Dept. of Gynecology, Oriental Medicine, Kyungwon University) ;
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Lee, Eun
(Dept. of Bioindustry and technology, College of Life Science & Natural Resources, Sangji University) ;
- Chang, Sung-Hwan (Dept. of Gynecology, Oriental Medicine, Kyungwon University)
- 발행 : 2006.02.28
초록
Purpose : This study was to investigate the effects of Dohongsamul-tang extract on the rat with an surgically induced endometriosis. Methods : Four weeks after the operation for inducing the endometriosis to a matured female rat, the normal hyperplasia of the transplanted endometrium was identified in anatomico-histological aspects. By dividing each of the control group and Dohongsamul-tang administered experimental group into 8 rats, Dohongsamul-tang concentrates were administered orally to the experimental group with 1g/1ml/200g everyday for 40 days and then images were taken from the macroscopic tissues which were transplanted to the mesenterium, and the concentrations of progesterone, estradiol, tumor necrosis