대한예방한의학회지 (Journal of Society of Preventive Korean Medicine)
- 제10권2호
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- Pages.51-62
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- 2006
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- 1226-7066(pISSN)
Rehmannia Radix의 IGF-II로 유도된 HIF-1 ${\alpha}$ 와 VEGF 발현 억제
Rehmannia Radix(RR) Extracts Inhibit IGF-II Induced VEGF and HIF-1 ${\alpha}$ Expressions in HaCaT Keratinocyte Cells
- Park, Ung (Dept. of Preventive Medicine, College of Traditional Korean Medicine, Kyunghee Univ.) ;
- Shin, Yong-Cheol (Dept. of Preventive Medicine, College of Traditional Korean Medicine, Kyunghee Univ.) ;
- Ko, Seong-Gyu (Dept. of Preventive Medicine, College of Traditional Korean Medicine, Kyunghee Univ.)
- 발행 : 2006.12.28
초록
Psoriasis is a chronic skin disease characterized by angiogenesis. It has been reported that growth factor as vascular endothelial growth factor(VEGF) and insulin like growth factor(IGF) II are overexpressed in psoriatic epidermis. To investigate the inhibitory effects of IGF-II induced VEGF and HIF-1