참고문헌
- Claus, R., Russwurm, S., Meisner, M., Kinscherf, R., and Deigner, H. P., Modulation of the ceramide level, a novel therapeutic concept? Curr. Drug Targets, 1, 185-205 (2000) https://doi.org/10.2174/1389450003349272
- Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P.G., Coso, O.A., Gutkind, S., and Spiegel, S., Suppression of ceramidemediated programmed cell death by sphingosine-1- phosphate. Nature, 381, 800-803 (1996) https://doi.org/10.1038/381800a0
- Edsall, L. C. and Spiegel, S., Enzymatic measurement of sphingosine 1-phosphate. Anal Biochem., 272, 80-86 (1999) https://doi.org/10.1006/abio.1999.4157
- French, K. J., Schrecengost, R. S., Lee, B. D., Zhuang, Y., Smith, S. N., Eberly, J. L., Yun, J. K., and Smith, C. D., Discovery and evaluation of inhibitors of human sphingosine kinase. Cancer Res., 63, 5962-5969 (2003)
- French, K. J., Upson, J. J., Keller, S. N., Zhuang, Y., Yun, J. K., and Smith, C. D., Antitumor activity of sphingosine kinase inhibitors. J. Pharmacol. Exp. Ther., 318, 596-603 (2006) https://doi.org/10.1124/jpet.106.101345
- Igarashi, Y., Hakomori, S., Toyokuni, T., Dean, B., Fujita, S., Sugimoto, M., Ogawa, T., el-Ghendy, K., and Racker, E., Effect of chemically well-defined sphingosine and its Nmethyl derivatives on protein kinase C and src kinase activities. Biochemistry, 28, 6796-6800 (1989) https://doi.org/10.1021/bi00443a002
- Kariya, Y., Kihara, A., Ikeda, M., Kikuchi, F., Nakamura, S., Hashimoto, S., Choi, C. H., Lee, Y. M., and Igarashi, Y., Products by the sphingosine kinase/sphingosine 1- phosphate (S1P) lyase pathway but not S1P stimulate mitogenesis. Genes Cells, 10, 605-615 (2005) https://doi.org/10.1111/j.1365-2443.2005.00862.x
- King, C. C., Zenke, F. T., Dawson, P. E., Dutil, E. M., Newton, A. C., Hemmings, B. A., and Bokoch, G. M., Sphingosine is a novel activator of 3-phosphoinositide-dependent kinase 1. J. Biol. Chem., 275, 18108-18113 (2000) https://doi.org/10.1074/jbc.M909663199
- Kono, K., Tanaka, M., Mizuno, T., Kodama, K., Ogita, T., and Kohama, T., B-535a, b and c, new sphingosine kinase inhibitors, produced by a marine bacterium; taxonomy, fermentation, isolation, physico-chemical properties and structure determination. J. Antibiot. (Tokyo), 53, 753-758 (2000) https://doi.org/10.7164/antibiotics.53.753
- Kono, K., Tanaka, M., Ono, Y., Hosoya, T., Ogita, T., and Kohama, T., S-15183a and b, new sphingosine kinase inhibitors, produced by a fungus. J. Antibiot. (Tokyo), 54, 415- 420 (2001) https://doi.org/10.7164/antibiotics.54.415
- Lee, M. J., Van Brocklyn, J. R., Thangada, S., Liu, C. H., Hand, A. R., Menzeleev, R., Spiegel, S., and Hla, T., Sphingosine 1- phosphate as a ligand for the G-protein-coupled receptor EDG-1. Science, 279, 1552-1555 (1996) https://doi.org/10.1126/science.279.5356.1552
- Mazurek, N., Megidish, T., Hakomori, S., and Igarashi, Y., Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response-a preliminary note. Biochem Biophys Res Commun., 198, 1-9 (1994) https://doi.org/10.1006/bbrc.1994.1001
- McDonald, O. B., Hannun, Y. A., Reynolds, C. H., and Sahyoun, N., Activation of casein kinase II by sphingosine. J. Biol. Chem., 266, 21773-21776 (1991)
- Megidish, T., White, T., Takio, K., Titani, K., Igarashi, Y., and Hakomori, S., The signal modulator protein 14-3-3 is a target of sphingosine- or N,N-dimethylsphingosine-dependent kinase in 3T3(A31) cells. Biochem. Biophys. Res. Commun., 216, 739-747 (1995) https://doi.org/10.1006/bbrc.1995.2684
- Ogretmen B. and Hannun Y. A., Updates on functions of ceramide in chemotherapy-induced cell death and in multidrug resistance. Drug Resist. Updat., 4, 368-377 (2001) https://doi.org/10.1054/drup.2001.0225
- Olivera, A. and Spiegel, S., Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature, 365, 557-560 (1993) https://doi.org/10.1038/365557a0
- Olivera, A., Kohama, T., Tu, Z., Milstien, S., and Spiegel, S., Purification and characterization of rat kidney sphingosine kinase. J. Biol. Chem., 273,12576-12583 (1998) https://doi.org/10.1074/jbc.273.20.12576
- Xia, P., Gamble, J. R., Wang, L., Pitson, S. M., Moretti, P. A., Wattenberg, B. W., D'Andrea, R. J., and Vadas, M. A., An oncogenic role of sphingosine kinase. Curr. Biol., 10, 1527- 1530 (2000) https://doi.org/10.1016/S0960-9822(00)00834-4
- Yatomi, Y., Ruan, F., Megidish, T., Toyokuni, T., Hakomori, S., and Igarashi, Y., N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets. Biochemistry, 35, 626-633 (1996) https://doi.org/10.1021/bi9515533