Korean Journal of Radiology

  • 제7권4호
  • /
  • Pages.267-274
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  • 2006
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  • 1229-6929(pISSN)
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  • 2005-8330(eISSN)
대한영상의학회 (The Korean Society of Radiology)
권호 표지

Risk Factors for Local Tumor Recurrence after Segmental Transarterial Chemoembolization for Hepatocellular Carcinoma: the Importance of Tumor Located in the Segmental Border Zone

  • Cho, Yun-Ku (Department of Radiology, Seoul Veterans Hospital) ;
  • Chung, Jin-Wook (Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine) ;
  • Ahn, Yong-Sik (Department of Radiology, Seoul Veterans Hospital) ;
  • Park, Yoon-Ok (Department of Radiology, Seoul Veterans Hospital) ;
  • Kim, Jae-Kyun (Department of Radiology, Seoul Veterans Hospital) ;
  • Byun, Jong-Hoon (Department of Internal Medicine, Seoul Veterans Hospital)
  • 발행 : 2006.12.31
⟨ 이전 논문 다음 논문 ⟩

초록

Objective: We wanted to evaluate whether tumors located in a segmental border zone are predisposed to local recurrence after performing segmental transarterial chemoembolization for hepatocellular carcinoma. Materials and Methods: Seventy-three hepatocellular carcinoma nodules were retrospectively analyzed for local tumor recurrence after performing segmental transarterial chemoembolization by using follow-up CT studies (median follow-up period: 20 months, range: 4-77 months). The tumors were divided into two groups according to whether the lesions were located at the segmental border zone (Group I) or not (Group II). Comparison of the tumor characteristics and chemoembolization methods between the two groups was performed using the chi-square test. The local recurrence rates were compared by Kaplan-Meyer method and analyzed with the log rank test. Results: Local tumor recurrence occurred for 25 hepatocellular carcinoma nodules (42.9%). The follow-up periods, tumor characteristics and chemoembolization methods between Groups I and II were comparable. The local recurrence rate was 64.0% (16/25) in Group I and 18.8% (9/48) in Group II. The difference was statistically significant on the univariate and multivariate analyses (p=0.000 for both). Conclusion: Tumor location in a segmental border zone was a significant risk factor for local tumor recurrence after performing segmental transarterial chemoembolization for hepatocellular carcinoma.

키워드

참고문헌

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