Asian-Australasian Journal of Animal Sciences

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Analysis on Association of a SNP in the Chicken OBR Gene with Growth and Body Composition Traits

  • Wang, Ying (College of Animal Science, Northeast Agricultural University) ;
  • Li, Hui (College of Animal Science, Northeast Agricultural University) ;
  • Zhang, YuanDan (Animal Genetics and Breeding Unit, the University of NewEngland, Armidale) ;
  • Gu, ZhiLiang (College of Animal Science, Northeast Agricultural University) ;
  • Li, ZhiHui (College of Animal Science, Northeast Agricultural University) ;
  • Wang, QiGui (College of Animal Science, Northeast Agricultural University)
  • Received : 2006.02.25
  • Accepted : 2006.08.19
  • Published : 2005.12.01
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Abstract

Leptin receptor (OBR) is a member of the class I cytokine receptor family. It signals mainly via the JAK/STAT pathway and plays an important role in regulating body energy storage and metabolism. This study was designed to investigate the effects of the OBR gene on chicken growth and body composition. Broiler lines selected divergently for or against abdominal fat were used. Primers for the exon9-region in the OBR gene were designed using chicken genomic sequences from the public genome domain. A C/A single nucleotide polymorphism (SNP) was found and its three genotypes (AA, AB and BB) were identified in this population. The results showed that the OBR polymorphism was associated with fatness traits, such as abdominal fat weight and abdominal fat percentage. This research suggests that OBR or a linked gene has effect on fat deposition in the chicken.

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References

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