Clinical and Experimental Pediatrics

The Korean Pediatric Society (대한소아청소년과학회)
권호 표지

Neonatal jaundice

신생아 황달

  • Lee, Sang Lak (Department of Pediatrics, Keimyung University School of Medicine)
  • 이상락 (계명대학교 의과대학 소아과학교실)
  • Received : 2005.12.01
  • Accepted : 2005.12.06
  • Published : 2006.01.15
Download PDF
⟨ Previous Next ⟩

Abstract

Jaundice is one of the most common gastrointestinal conditions found in neonatal period, and most jaundice is benign. But because of the possibility of bilirubin toxicity, every newborn infants must be examined to identify the development of severe hyperbilirubinemia. To prevent the development of severe hyperbilirubinemia, promote and support successful breast-feeding, perform a systemic assessment before discharge for the risk of severe hyperbilirubinemia, provide early and close follow-up program, and treat with phototherapy or exchange transfusion or other therapeutic modalities, if indicated, are recommended.

Keywords

References

  1. Stoll BJ, Kliegman RM. Jaundice and hyperbilirubinemia in the newborn. In : Behrman RE, Kliegman RM, Jenson HB, editors. Nelson Textbook of Pediatrics. 17th ed. Philadelphia : WB Saunders Co, 2004:592-9
  2. American Academy of Pediatrics. Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics 2004;114:297-316 https://doi.org/10.1542/peds.114.1.297
  3. Maisels MJ. Jaundice. In : MacDonald MG, Mullett MD, Seshia MMK, editors. Avery's Neonatology; pathophysiology & management of the newborn. 6th ed. Philadelphia : Lippincott Williams & Wilkins, 2005:768-846
  4. Ahn HS. Textbook of pediatrics. 8th ed. Seoul : Daehan Printing & Publishing Co, 2004:343
  5. Maisels MJ. Neonatal jaundice. In : Avery GB, editor. Neonatology.2nd ed. Philadelphia : JB Lippincott, 1981:484
  6. Horiguchi T, Bauer C. Ethnic differences in neonatal jaundice; comparison of Japanese and Caucasian newborn infants. Am J Obstet Gynecol 1975;121:71-4 https://doi.org/10.1016/0002-9378(75)90978-3
  7. Gartner LM. Neonatal jaundice. Pediatr Rev 1994;15:422-32
  8. MacMahon JR, Stevenson DK, Oski FA. Physiologic jaundice. In : Taeusch HW, Ballard RA, editors. Avery's Diseases of the Newborn. 7th ed. hiladelphia : WB Saunders Co, 1998:1003-7
  9. Semmekrot BA, de Vries MG, Gerrits GP, van Wieringen PM. Optimal breastfeeding to prevent hyperbilirubinemia in healthy, term newborns. Ned Tijdschr Geneeskd 2004;148: 2016-9
  10. Maisels MJ, Gifford K. Normal serum bilirubin levels in the newborn and the effect of breast-feeding. Pediatrics 1986;78:837-43
  11. Freeman J, Lesko SM, Mitchell AA, Epstein MF, Shapiro S. Hyperbilirubinemia following exposure to pancuronium bromide in newborns. Dev Pharmacol Ther 1990;14:209-15
  12. Lambert GH, Muraskas J, Anderson CL, Myers TF. Direct hyperbilirubinemia associated with chloral hydrate administration in the newborn. Pediatrics 1990;86:277-81
  13. Robertson A, Carp W, Broderson R. Bilirubin displacing effect effect of drugs used in neonatology. Acta Paediatr Scand 1991;80:1119-27 https://doi.org/10.1111/j.1651-2227.1991.tb11798.x
  14. Dennery PA, Seidman DS, Stevenson DK. Neonatal hyperbilirubinemia. N Engl J Med 2001;344:581-90 https://doi.org/10.1056/NEJM200102223440807
  15. Grobler JM, Mercer MJ. Kernicterus associated with elevated predominantly direct-reacting bilirubin. S Afr Med J 1997;87:1146.
  16. Vohr BR. New approaches to assessing the risks of hyperbilirubinemia. Clin Perinatol 1990;17:293-306 https://doi.org/10.1016/S0095-5108(18)30569-4
  17. Maisels MJ. Jaundice. In : Avery GB, Fletcher MA, Mac- Donald MG, editors. Neonatology; pathophysiology & management of the newborn. 5th ed. Philadelphia : Lippincott Williams & Wilkins, 1999:765-819
  18. Kappas A, Drummond GS, Manola T, Petmezaki S, Valaes T. Sn-protoporphyrin use in the management of hyperbilirubinemia in term newborns with direct Coombs-positive ABO incompatibility. Pediatrics 1988; 81:485-97
  19. Valaes T, Drummond GS, Kappas A. Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Snprotoporphyrin. Pediatrics 1998;101:E1
  20. Martinez JC, Garcia HO, Otheguy LE, Drummond GS, Kappas A. Control of severe hyperbilirubinemia in full-term newborns with the inhibitor of bilirubin production Snmesoporphyrin. Pediatrics 1999;103:1-5 https://doi.org/10.1542/peds.103.1.1
  21. Kappas A, Drummond GS, Munson DP, Marshall JR. Snmesoporphyrin interdiction of severe hyperbilirubinemia in Jehovah's Witness newborns as an alternative to exchange transfusion. Pediatrics 2001;108:1374-7 https://doi.org/10.1542/peds.108.6.1374
  22. Sato K, Hara T, Kondo T, Iwao H, Honda S, Ueda K. High-dose intravenous gammaglobulin therapy for neonatal immune haemolytic jaundice due to blood group incompatibility. Acta Paediatr Scand 1991;80:163-6 https://doi.org/10.1111/j.1651-2227.1991.tb12023.x
  23. Rübo J, Albrecht K, Lasch P, Laufkötter E, Leititis J, Marsan D, et al. High-dose intravenous immune globulin therapy for hyperbilirubinemia caused by Rh hemolytic disease. J Pediatr 1992;121:93-7 https://doi.org/10.1016/S0022-3476(05)82551-X
  24. Cho YJ, Kim CS, Lee SL. The effect of high-dose intravenous immune globulin in the treatment of neonatal immune hemolytic jaundice unresponsive to phototherapy. Kor J Perinatol 1999;19:176-82 https://doi.org/10.1038/sj.jp.7200248
  25. Alcock GS, Liley H. Immunoglobulin infusion for isoimmune haemolytic jaundice in neonates. Cochrane Database Syst Rev 2002;3:CD003313
  26. Martinez JC, Maisels MJ, Otheguy L, Garcia H, Savorani M, Mogni B, et al. Hyperbilirubinemia in the breast-fed newborn : a controlled trial of four interventions. Pediatrics 1993;91:470-3
  27. Alkalay AL, Simmons CF. Hyperbilirubinemia guidelines in newborn infants. Pediatrics 2005;115:824-5 https://doi.org/10.1542/peds.2004-2442