Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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수두백신의 최신지견

Update in varicella vaccination

  • 오성희 (한양대학교 의과대학 소아과학교실)
  • Oh, Sung Hee (Department of Pediatrics, College of Medicine, Hanyang University)
  • 투고 : 2006.02.20
  • 심사 : 2006.02.22
  • 발행 : 2006.03.15
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초록

Varicella, which is mostly a benign disease, but also can cause considerable health burden in the community, can be prevented by immunization with live attenuated varicella vaccine. Higher uptake of varicella vaccine by universal immunization in North America has apparently been associated with decline in the number of reported cases of varicella, varicella-related hospitalizations, and the number of deaths caused by complications of varicella. On the contrary, there has been some reluctance in endorsing varicella vaccine for universal immunization in most of European countries. Concerns include unanticipated outbreaks of varicella among vaccine recipients, risk of varicella among unvaccinated adults, risk of herpes zoster among vaccinees as well as unvaccinees. Recently developed measles, mumps, rubella, and varicella combination vaccine and herpes zoster vaccine that may be licensed in the upcoming years may be the solution for varicella vaccine to be utilized in a greater scale. In Korea several varicella vaccine products have been utilized since late 1980. The adoption of varicella vaccine for universal immunization since 2005 along with the changing view in varicella prevention strategy mandates more studies for immunogenecity and efficacy of varicella vaccines as well as more surveillance to delineate the changes in epidemiology of varicella in Korea.

키워드

참고문헌

  1. Takahashi M. Effectiveness of live varicella vaccine. Expert Opin Biol Ther 2004;4:199-216 https://doi.org/10.1517/14712598.4.2.199
  2. Hall S, Maupin T, Seward J, Jumaan AO, Peterson C, Goldman G, et al. Second varicella infections : Are they more common than previously thought- Pediatrics 2002;19:1068-73
  3. Davies HD, McGeer A, Schwartz B, Green K, Cann D, Simor AE, et al. Invasive Group A streptococcal infections in Ontario, Canada. N Engl J Med 1996;335:547-54 https://doi.org/10.1056/NEJM199608223350803
  4. Health Canada. Proceedings of the national varicella consensus conference. CCDR 1999;25:1-29
  5. Meyer PA, Seward JF, Jumaan AO, Wharton M. Varicella mortality : trends before vaccine licensure in the United States, 1970-1994. J Infect Dis 2000;182:383-90 https://doi.org/10.1086/315714
  6. White CJ, Kuter BJ, Hilderbrand CS, Isganitis KL, Matthews H, Miller WJ, et al. Varicella vaccine(Varivax) in healthy children and adolescents : results from clinical trials, 1987-89. Pediatrics 1991;87:604-10
  7. Weibel RE, Kuter BJ, Neff BJ, Rothenberger CA, Fitzgerald AJ, Connor KA, et al. Live Oka/Merck varicella vaccine in healthy children. Further clinical and laboratory assessment. JAMA 1985;254:2435-9 https://doi.org/10.1001/jama.254.17.2435
  8. Varis T, Vesikari T. Efficacy of high-titer live attenuated varicella vaccine in healthy young children. J Infect Dis 1996;174 Suppl 3:S330-4 https://doi.org/10.1093/infdis/174.Supplement_3.S330
  9. Katsushima N, Yazaki N, Sakamoto M. Effect and followup study on varicella vaccine. Biken J 1984;27:51-8
  10. Morales-Castillo ME, Alvarez-Muñoz MT, Solórzano-Santos F, González-Robledo R, Jasso-Gutiérrez L, Muñoz-Hernández O. Live varicella vaccine in both immunocompromised and healthy children. Arch Medl Res 2002;31:85-7
  11. Johnson CE, Stancin T, Fattlar D, Rome LP, Kumar ML. A long-term prospective study of varicella vaccine in healthy children. Pediatrics 1997;100:761-6 https://doi.org/10.1542/peds.100.5.761
  12. Sheffer R, Segal D, Rahamani S, Datal H, Linhart Y, Stein M, et al. Effectiveness of the Oka/GSK attenuated varicella vaccine for the prevention of chickenpox in clinical practice in Israel. Pediatr Infect Dis J 2005;24:434-7 https://doi.org/10.1097/01.inf.0000160947.89942.30
  13. Galil K, Lee B, Strine T, Carraher C, Baughman AL, Eaton M, et al. Outbreak of varicella at a day-care center despite vaccination. N Engl J Med 2002;347:1909-15 https://doi.org/10.1056/NEJMoa021662
  14. Vazquez M, LaRussa PS, Gershon AA, Niccolai LM, Nuehlenbein CE, Steinberg SP, et al. Effectiveness over time of varicella vaccine. JAMA 2004;291:851-5 https://doi.org/10.1001/jama.291.7.851
  15. Galil K, Fair E, Mountcastle N, Britz P, Seward J, Younger age at vaccination may increase risk of varicella vaccine failure. J infect Dis 2002;186:102-5 https://doi.org/10.1086/341089
  16. Lee BR, Feaver SL, Miller CA, Hedberg CW, Ehresmann KR. An elementary school outbreak of varicella attributed to vaccine failure : policy implications. J Infect Dis 2004;190: 477-83
  17. Li, Shu, Chan ISF, Matthews H, Heyse J, Chan CY. Inverse relationship between six week postvaccination varicella antibody response to vaccine and likelihood of long term breakthrough infection. Pediatr Infect Dis J 2002;21:337-42 https://doi.org/10.1097/00006454-200204000-00014
  18. Grose C. Varicella vaccination of children in the United States : Assessment after the first decade 1995-2005. J Clin Virol 2005;33:89-95 https://doi.org/10.1016/j.jcv.2005.02.003
  19. Arvin AM, Gershon AA. Live attenuated varicella vaccine. 1996 Annu Rev Microbiol 1996;50:59-100 https://doi.org/10.1146/annurev.micro.50.1.59
  20. Seward J, Watson BM, Peterson CL, Mascola L, Pelosi JW, Zhang JX, et al. Varicella disease after introduction of varicella vaccine in the United States, 1995-2000. JAMA 2002;287:606-11 https://doi.org/10.1001/jama.287.5.606
  21. Zhou F, Harpaz R, Jumaan AO, Winston CA, Shefer A. Impact of varicella vaccination on health care utilization. JAMA 2005;294:797-802 https://doi.org/10.1001/jama.294.7.797
  22. Nguyen HQ, Jumaan AO, Seward JF. Decline in mortality due to varicella after implementation of varicellavaccination in the United States. N Engl J Med 2005;352:450-8. https://doi.org/10.1056/NEJMoa042271
  23. LaRussa P, Steinberg S, Gershon AA. Varicella vaccine for immunocompromised children : results of collaborativestudies in the United States and Canada. J Infect Dis 1996;174: S320-3 https://doi.org/10.1093/infdis/174.Supplement_3.S320
  24. Goldman GS. Incidence of herpes zoster among children and adolescents in a community with moderate varicella vaccination coverage. Vaccine 2003;21:4243-9 https://doi.org/10.1016/S0264-410X(03)00459-6
  25. Thomas SL, Wheeler JG, Hall AJ. Contacts with varicella or with children and protection against herpes zoster in adults : a case-control study. Lancet 2002;360:678-82 https://doi.org/10.1016/S0140-6736(02)09837-9
  26. Brisson M, Gay NJ, Edmunds WJ, Andrews NJ. Exposure to varicella boosts immunity to herpes-zoster : implications for mass vaccination against chickenpox. Vaccine 2002;20:2500-7 https://doi.org/10.1016/S0264-410X(02)00180-9
  27. Volpi A. Varicella immunization and herpes zoster. Herpes 2005;12:59
  28. Brisson M, Edmunds WJ. Varicella vaccination in England and Wales : cost-utility analysis. Arch Dis Child 2003;88: 862-9 https://doi.org/10.1136/adc.88.10.862
  29. Brisson and Edmuds. The cost-effectiveness of varicella vaccination in Canada. Vaccine 2002;20:1113-25 https://doi.org/10.1016/S0264-410X(01)00437-6
  30. Shinefield H, Black S, Digilio L, Reisinger K, Blatter M, Gress JO, et al. Evaluation of a quadrivalent measles, mumps, rubella and varicella vaccine inhealthy children. Pediatr Infect Dis J 2005;24:665-9 https://doi.org/10.1097/01.inf.0000172902.25009.a1
  31. Reisinger KS, Brown ML, Xu J, Sullivan BJ, Marshall GS, Nauert B, et al. A combination measles, mumps, rubella, and varicella vaccine(ProQuad) given to 4-to 6-year-old healthy children vaccinated previously with M-M-RII and Varivax. Pediatrics 2006;117:265-72 https://doi.org/10.1542/peds.2005-0092
  32. Kang JH, Kim JH, Suh BK. The Immunogenicity and safety study of 47 passaged Oka strain live attenuated varicella vaccine in healthy children. Korean J Pediatr Infect Dis 1997;4:257-64 https://doi.org/10.14776/kjpid.1997.4.2.257
  33. Kim DJ, Park HS, Lee SY, Park KS, Kim TK, Song YH, et al. Epidemiology of varicella in Korea based on pediatrician's office practice. J Korean Pediatr Soc 1997;40:73-81
  34. Kim MR, Park JS, Kim DH, Lee HR, Park CY. A clinical and epidemiologic study on varicella in children. Korean J Pediatr Inf Dis 1998;5:88-95
  35. Watson B, Seward J, Yang A, Witte P, Lutz J, Chan C, et al. Postexposure effectiveness of varicella vaccine. Pediatrics 2000;105:85-8 https://doi.org/10.1542/peds.105.6.e85