References
- Abbott, N. J. (2000) Inflammatory mediators and modulation of blood-brain barrier permeability. Cell. Mol. Neurobiol. 20, 131-147 https://doi.org/10.1023/A:1007074420772
- Abbott, N. J. (2002) Astrocyte-endothelial interactions and bloodbrain barrier permeability. J. Anat. 200, 629-638 https://doi.org/10.1046/j.1469-7580.2002.00064.x
- Abbott, N. J. (2004) Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology. Neurochem. Int. 45, 545-552 https://doi.org/10.1016/j.neuint.2003.11.006
- Anderson, J. M., Fanning, A. S., Lapierre, L. and Van Itallie, C. M. (1995) Zonula occludens (ZO)-1 and ZO-2: membrane-associated guanylate kinase homologues (MAGUKs) of the tight junction. Biochem. Soc. Trans. 23, 470-475 https://doi.org/10.1042/bst0230470
- Bandopadhyay, R., Orte, C., Lawrenson, J. G., Reid, A. R., De Silva, S. and Allt, G. (2001) Contractile proteins in pericytes at the blood-brain and blood-retinal barriers. J. Neurocytol. 30, 35-44 https://doi.org/10.1023/A:1011965307612
- Bauer, H. C. and Bauer, H. (2000) Neural induction of the bloodbrain barrier: still an enigma. Cell. Mol. Neurobiol. 20, 13-28 https://doi.org/10.1023/A:1006939825857
- Begley, D. J. and Brightman, M. W. (2003) Structural and functional aspects of the blood-brain barrier. Prog. Drug Res. 61, 40-78
- Braun, L. D., Cornford, E. M. and Oldendorf, W. H. (1980) Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult. J. Neurochem. 34, 147-152 https://doi.org/10.1111/j.1471-4159.1980.tb04633.x
- Brightman, M. W. and Reese, T. S. (1969) Junctions between intimately apposed cell membranes in the vertebrate brain. J. Cell. Biol. 40, 648-677 https://doi.org/10.1083/jcb.40.3.648
- Brillault, J., Berezowski, V., Cecchelli, R. and Dehouck, M. P. (2002) Intercommunications between brain capillary endothelial cells and glial cells increase the transcellular permeability of the blood brain barrier during ischaemia. J. Neurochem. 83, 807-817 https://doi.org/10.1046/j.1471-4159.2002.01186.x
- Davson, H. and Oldendorf, W. H. (1967) Transport in the central nervous system. Proc. R. Soc. Med. 60, 326-328
- Dehouck, M. P., Meresse, S., Delorme, P., Fruchart, J. C. and Cecchelli, R. (1990) An easier, reproducible, and massproduction method to study the blood-brain barrier in vitro. J. Neurochem. 54, 1798-1801 https://doi.org/10.1111/j.1471-4159.1990.tb01236.x
- Dehouck, M. P., Vigne, P., Torpier, G., Breittmayer, J. P., Cecchelli, R. and Frelin, C. (1997) Endothelin-1 as a mediatore of endothelial cell-percyte interactions in bovine brain capillaries. J. Cereb. Blood Flow Metab. 17, 464-469 https://doi.org/10.1097/00004647-199704000-00012
- Deli, M. A., Descamps, L., Dehouck, M. P., Cecchelli, R., Joo, F., Abraham, C. S. and Torpier, G. (1995) Exposure of tumor necrosis factor-a to luminal membrane of bovine capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress formation of actin. J. Neurosci. Res. 41, 717-726 https://doi.org/10.1002/jnr.490410602
- Dermietzel, R. and Krause, D. (1991) Molecular anatomy of the blood-brain barrier as defined by immunocytochemistry. Int. Rev. Cytol. 12, 57-109
- de Vries, H. E. And Dijkstra, D. D. (2004) Mononuclear phagocytes at the blood-brain barrier in multiple sclerosis; in Blood-Spinal Cord and Brain Barriers in Health and Disease, Sharma, H. S. and Westman, J. (eds.) pp. 409-417, Elsevier, San Diego, USA
- Dore-Duffy, P., Owen, C., Balabanov, R., Murphy, S., Beaumont, T. and Rafols, J. A. (2000) Pericyte migration from the vascular wall in response to traumatic brain injury. Microvasc. Res. 60, 55-69 https://doi.org/10.1006/mvre.2000.2244
- Fanning, A. S., Jameson, B. J., Jesaitis, L. A. and Anderson, J. M. (1998) The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J. Biol. Chem. 273, 29745-29753 https://doi.org/10.1074/jbc.273.45.29745
- Farkas, E. and Luiten, P. G. (2001) Cerebral microvascular pathology in aging and Alzheimer's disease. Prog. Neurobiol. 64, 575-611 https://doi.org/10.1016/S0301-0082(00)00068-X
- Fenstermacher, J., Gross, P., Sposito, N., Acuff, V., Pettersen, S. and Gruber, K. (1988) Structural and functional variations in capillary systems within the brain. Ann. N.Y. Acad. Sci. 529, 21-30 https://doi.org/10.1111/j.1749-6632.1988.tb51416.x
- Fischer, S., Wobben, M., Kleinstuck, J., Renz, D. and Schaper, W. (2000) Effect of astroglial cells on hypoxia-induced permeability in PBMEC cells. Am. J. Physiol. Cell. Physiol. 279, 935-944 https://doi.org/10.1152/ajpcell.2000.279.4.C935
- Furuse, M., Fujita, K., Hiiragi, T., Fujimoto, K. and Tsukita, S.(1998) Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occluding. J. Cell Biol. 141, 1539-1550 https://doi.org/10.1083/jcb.141.7.1539
- Gonul, E., Duz, B., Kahraman, S., Kayali, H., Kubar, A. and Timurkaynak, E. (2002) Early pericyte response to brain hypoxia in cats: an ultrastructural study. Microvasc. Res. 64, 116-119 https://doi.org/10.1006/mvre.2002.2413
- Gursoy-Ozdemir, Y., Qiu, J., Matsuoka, N., Bolay, H., Bermpohl, D., Jin, H., Wang, X., Rosenberg, G. A., Lo, E. H. and Moskowitz, M. A. (2004) Cortical spreading depression activates and upregulates MMP-9. J. Clin. Investig. 113, 1447-1455 https://doi.org/10.1172/JCI200421227
- Haskins, J., Gu, L., Wittchen, E. S. and Hibbard, J. (1998) Stevenson BR. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occluding. J. Cell Biol. 141, 199-208 https://doi.org/10.1083/jcb.141.1.199
- Hayashi, Y., Nomura, M., Yamagishi, S., Harada, S., Yamashita, J. and Yamamoto, H. (1997) Induction of various blood-brain barrier properties in non-neural endothelial cells by close apposition to co-cultured astrocytes. Glia 19, 13-26 https://doi.org/10.1002/(SICI)1098-1136(199701)19:1<13::AID-GLIA2>3.0.CO;2-B
- Hickey, W. F. (2001) Basic principles of immunological surveillance of the normal central nervous system. Glia 36, 118-124
- Hirase, T., Staddon, J. M., Saitou, M., Ando-Akatsuka, Y., Itoh, M., Furuse, M., Fujimoto, K., Tsukita, S. and Rubin, L. L. (1997) Occludin as a possible determinant of tight junction permeability in endothelial cells. J. Cell Sci. 110, 1603-1613
- Hori, S., Ohtsuki, S., Hosoya, K., Nakashima, E. and Terasaki, T. (2004) A pericyte- derived angiopoietin-1 multimeric complex induces occluding gene expression in brain capillary endothelial cells through Tie-2 activation in vitro. J. Neurochem. 89, 503-513 https://doi.org/10.1111/j.1471-4159.2004.02343.x
- Huber, J. D., Egleton, R. D. and Davis, T. P. (2001) Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier. Trends Neurosci. 24, 719-725 https://doi.org/10.1016/S0166-2236(00)02004-X
- Pardridge, W. M. (2005) The blood-brain barrier: bottle neck in brain drug development. NeuroRx 2, 3-14 https://doi.org/10.1602/neurorx.2.1.3
- Hurst, R. D. and Fritz, I. B. (1996) Properties of an immortalized vascular endothelial/glioma cell co-culture model of the bloodbrain barrier. J. Cell. Physiol. 167, 81-88 https://doi.org/10.1002/(SICI)1097-4652(199604)167:1<81::AID-JCP9>3.0.CO;2-8
- Iadecola, C. (1993) Regulation of the cerebral microcirculation during neural activity: is nitric oxide the missing link? Trends Neurosci. 16, 206-214 https://doi.org/10.1016/0166-2236(93)90156-G
- Itoh, M., Furuse, M., Morita, K., Kubota, K., Saitou, M. and Tsukita, S. (1999) Direct binding of three tight junctionassociated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J. Cell Biol. 147, 1351-1363 https://doi.org/10.1083/jcb.147.6.1351
- Janzer, R. C. and Raff, M. C. (1997) Astrocytes induce bloodbrain barrier properties in endothelial cells. Nature 325, 253-257
- Kacem, K., Lacombe, P., Seylaz, J. and Bonvento, G. (1998) Structural organization of the perivascular astrocyte endfeet and their relationship with the endothelial glucose transporter: a confocal microscopy study. Glia 23, 1-10 https://doi.org/10.1002/(SICI)1098-1136(199805)23:1<1::AID-GLIA1>3.0.CO;2-B
- Kniesel, U. and Wolburg, H. (2000) Tight junctions of the bloodbrain barrier. Cell. Mol. Neurobiol. 20, 57-76 https://doi.org/10.1023/A:1006995910836
- Krum, J. M., Kenyon, K. L. and Rosenstein, J. M. (1997) Expression of blood-brain barrier characteristics following neuronal loss and astroglial damage after administration of anti-Thy-1 immunotoxin. Exp. Neurol. 146, 33-45 https://doi.org/10.1006/exnr.1997.6528
- Kuchler-Bopp, S., Delanoy, J. P., Artault, J. C., Zaepfel, M. and Dietrich, J. R. (1999) Astrocytes induce several blood-brain barrier properties in non-neural endothelial cells. Neuroreport 10, 1347-1353 https://doi.org/10.1097/00001756-199904260-00035
- Lee, E. J., Hung, Y. C. and Lee, M. Y. (1999) Early alterations in cerebral hemodynamics, brain metabolism and blood-brain barrier permeability in experimental intracerebral hemorrhage. J. Neurosurg. 91, 1013-1019 https://doi.org/10.3171/jns.1999.91.6.1013
- Lee, S. W., Kim, W. J., Choi, Y. K., Song, H. S., Son, M. J., Gelman, I. H., Kim, Y. J. and Kim, K. W. (2003) SSeCKS regulates angiogenesis and tight junction formation in bloodbrain barrier. Nat. Med. 9, 900-906 https://doi.org/10.1038/nm889
- Leybaert, L. (2005) Neurobarrier coupling in the brain: a partner of neurovascular and neurometabolic coupling? J. Cereb. Blood Flow Metab. 25, 2-16 https://doi.org/10.1038/sj.jcbfm.9600001
- Machein, M. R., Kullmer, J., Fiebich, B. L., Plate, K. H. and Warnke, P. C. (1999) Vascular endothelial growth factor expression, vascular volume, and capillary permeability in human brain tumors. Neurosurgery 44, 732-740 https://doi.org/10.1097/00006123-199904000-00022
- Mark, K. S. and Davis, T. (2002) Cerebral microvascular changes in permeability and tight junctions induced by hypoxiareoxygenation. Am. J. Physiol- Heart C. 282, 1485-1494 https://doi.org/10.1152/ajpheart.00645.2001
- McAllister, M. S. (2001) Mechanisms of glucose transporter at the blood-brain barrier: an in vitro study. Brain Res. 409, 20-30
- Mi, H., Haeberle, H. and Barres, B. A. (2001) Induction of astrocyte differentiation by endothelial cells. J. Neurosci. 21, 1538-1547 https://doi.org/10.1523/JNEUROSCI.21-05-01538.2001
- Oldendorf, W. H., Conford, M. E. and Brown, W. J. (1977) The large apparent work capability of the blood-brain barrier: a study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat. Ann. Neurol. 1, 409-417 https://doi.org/10.1002/ana.410010502
- Orte, C., Lawrenson, J. G., Finn, T. M., Reid, A. R. and Alit, G. A. (1999) Comparison of blood-brain barrier and blood-nerve barrier endothelial cell markers. Anat. Embryol. (Berl) 199, 509-517 https://doi.org/10.1007/s004290050248
- Oztas, B., Akgul, S. and Arslan, F. B. (2004) Influence of surgical pain stress on the blood-brain barrier permeability in rats. Life Sci. 74, 1973-1979 https://doi.org/10.1016/j.lfs.2003.07.054
- Pardridge, W. M. (1999) Blood-brain barrier biology and methodology. J. Neurovirol. 5, 556-569 https://doi.org/10.3109/13550289909021285
- Peridsky, Y., Ghorpade, A., Rasmussen, J., Limoges, J., Liu, X. J., Stins, M., Fiala, M., Way, D., Kim, K. S., Witte, M. H., Weinand, M., Carhart, L., Gendelman, H. E. (1999) Microglial and astrocyte chemokines regulate monocyte migration through the blood-brain barrier in human immunodeficiency virus-1encephalitis. Am. J. Pathol. 15, 1599-1611
- Petty, M. A. and Lo, E. H. (2002) Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation. Prog. Neurobiol. 68, 311-323 https://doi.org/10.1016/S0301-0082(02)00128-4
- Rascher, G., Fischmann, A., Kruger, S., Duffner, F., Grote, E. H. and Wolburg, H. (2002) Extracellular matrix and the bloodbrain barrier in glioblastoma multiforme: Spatial segregation of tenascin and agrin. Acta Neuropathol. 104, 85-91 https://doi.org/10.1007/s00401-002-0524-x
- Reese, T. S. and Karnovsky, M. J. (1967) Fine structural localization of a blood-brain barrier to exogenous peroxidase. J. Cell Biol. 34, 207-217 https://doi.org/10.1083/jcb.34.1.207
- Reichert, M., Muller, T. and Hunziker, W. (2000) The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin-Darby canine kidney cells. Evidence for a role of betacatenin/Tcf/Lef signaling. J. Biol. Chem. 275, 9492-9500
- Risau, W. and Wolburg, H. (1990) Development of blood-brain barrier. Trends Neurosci. 13, 174-178 https://doi.org/10.1016/0166-2236(90)90043-A
- Schinkel, A. H. (1999) P-glycoprotein, a gatekeeper in the bloodbrain barrier. Adv. Drug Deliv. Rev. 36, 179-194 https://doi.org/10.1016/S0169-409X(98)00085-4
- Schlageter, K. E., Molnar, P., Lapin, G. D. and Groothuis, D. R. (1999) Microvessel organization and structure in experimental brain tumor: microvessel populations with distinctive structural and functional properties. Microvasc. Res. 58, 312-328 https://doi.org/10.1006/mvre.1999.2188
- Schroeter, M. L., Mertsch, K., Giese, H., Muller, S., Sporbert, A., Hickel, B. and Blasig, I. E. (1999) Astrocytes enhance radical defence in capillary endothelial cells constituting the bloodbrain barrier. FEBS Lett. 449, 241-244 https://doi.org/10.1016/S0014-5793(99)00451-2
- Schwaninger, M., Sallmann, S., Petersen, N., Schneider, A., Prinz, S., Libermann, T. A. and Spranger, M. (1999) Bradykinin induces interleukin-6 expression in astrocytes through activation of nuclear factor-kB. J. Neurochem. 73, 1461-1466 https://doi.org/10.1046/j.1471-4159.1999.0731461.x
- Sedlakova, R., Shivers, R. R. and Del Maestro, R. F. (1999) Ultrastructure of the blood-brain barrier in the rabbit. J. Submicronsc. Cytol. Pathol. 31, 149-161
- Song, H. S., Son, M. J., Lee, Y. M., Kim, W. J., Lee, S. W., Kim, C. W. and Kim, K. W. (2002) Oxygen tension regulates the maturation of the blood-brain barrier. Biochem. Biophys. Res. Commun. 290, 325-331 https://doi.org/10.1006/bbrc.2001.6205
- Thurston, G., Suri, C., Smith, K., McClain, J., Sato, T. N., Yancopoulos, G. D. and McDonald, D. M. (1999) Leakageresistant blood vessels in mice transgenically overexpressing angiopoietin-1. Science 286, 2511-2514 https://doi.org/10.1126/science.286.5449.2511
- Wardlaw, J. M., Sandercock, P. A., Dennis, M. S. and Starr, J. (2003) Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia? Stroke 34, 806-812 https://doi.org/10.1161/01.STR.0000058480.77236.B3
- Wolburg, H. (2006) The endothelial frontier; in Blood-Brain Interfaces-from Ontogeny to Artificial Barriers, Dermietzel, R., Spray, D. and Nedergaard, M. (eds.) pp. 77-107, Wiley-VCH, Weinheim, Germany
- Wolburg, H. and Lippoldt, A. (2002) Tight junctions of the bloodbrain barrier. Vasc. Pharmacol. 38, 323-337 https://doi.org/10.1016/S1537-1891(02)00200-8
- Xu, J. and Ling, E. A. (1994) Studies of the ultrastructure and permeability of the blood-brain barrier in the developing corpus callosum in postnatal rat brain using electron dense tracers. J. Anat. 84, 227-237
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- Oxidized low density lipoprotein-induced senescence of retinal pigment epithelial cells is followed by outer blood–retinal barrier dysfunction vol.44, pp.5, 2012, https://doi.org/10.1016/j.biocel.2012.02.005
- Quantitative Proteomics Reveals β2 Integrin-mediated Cytoskeletal Rearrangement in Vascular Endothelial Growth Factor (VEGF)-induced Retinal Vascular Hyperpermeability vol.15, pp.5, 2016, https://doi.org/10.1074/mcp.M115.053249
- SPARC expression by cerebral microvascular endothelial cells in vitro and its influence on blood-brain barrier properties vol.13, pp.1, 2016, https://doi.org/10.1186/s12974-016-0657-9
- Permeability assessment of the focused ultrasound-induced blood–brain barrier opening using dynamic contrast-enhanced MRI vol.55, pp.18, 2010, https://doi.org/10.1088/0031-9155/55/18/012
- Astrocyte, the star avatar: redefined vol.33, pp.3, 2008, https://doi.org/10.1007/s12038-008-0060-5
- The brain tumor microenvironment vol.59, pp.8, 2011, https://doi.org/10.1002/glia.21136
- Pathogenesis, diagnosis and treatment of neuromyelitis optica: Changing concept of an old disease vol.1, pp.3, 2010, https://doi.org/10.1111/j.1759-1961.2010.00011.x
- ATP-sensitive potassium channels: A promising target for protecting neurovascular unit function in stroke vol.37, pp.2, 2010, https://doi.org/10.1111/j.1440-1681.2009.05190.x
- Investigation of barrier characteristics in the hyaloid-retinal vessel of zebrafish vol.89, pp.6, 2011, https://doi.org/10.1002/jnr.22607
- Interaction between pericytes and endothelial cells leads to formation of tight junction in hyaloid vessels vol.36, pp.5, 2013, https://doi.org/10.1007/s10059-013-0228-1
- Meteorin regulates angiogenesis at the gliovascular interface vol.56, pp.3, 2008, https://doi.org/10.1002/glia.20600
- The role of amino acid transporters in GSH synthesis in the blood–brain barrier and central nervous system vol.61, pp.3, 2012, https://doi.org/10.1016/j.neuint.2012.05.019
- Neural crest derivatives in ocular development: Discerning the eye of the storm vol.105, pp.2, 2015, https://doi.org/10.1002/bdrc.21095
- Role of Inflammation in Diabetic Retinopathy vol.19, pp.4, 2018, https://doi.org/10.3390/ijms19040942
- Signaling-chemokine axis network in brain as a sanctuary site for metastasis vol.234, pp.4, 2018, https://doi.org/10.1002/jcp.27305