Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Serum Parvovirus Antibody Titers among Healthy Adult Dogs in Korea

국내 성견의 개 파보바이러스에 대한 항체가 조사

  • Jeoung, Seok-Young (School of Veterinary Medicine, Kangwon National University) ;
  • Kim, Doo (School of Veterinary Medicine, Kangwon National University) ;
  • Ahn, So-Jeo (School of Veterinary Medicine, Kangwon National University) ;
  • Pak, Son-Il (School of Veterinary Medicine, Kangwon National University)
  • 정석영 (강원대학교 수의학부대학) ;
  • 김두 (강원대학교 수의학부대학) ;
  • 안소저 (강원대학교 수의학부대학) ;
  • 박선일 (강원대학교 수의학부대학)
  • Published : 2006.09.30
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Abstract

This study was performed to monitor the level of serum canine parvovirus(CPV) antibody titers in adult dogs throughout the Korea from January 2003 to April 2004. A total of clinically healthy 885 dogs between 1 year and 17 years old were included in this study. Serum antibody titers against CPV were measured by means of hemagglutination inhibition(HI) titers at the time dogs were brought to the hospital for revaccination. Most of dogs had been primarily vaccinated or previously revaccinated. Dogs were grouped by age, breed, sex, and primary vaccination and revaccination to determine whether these factors were associated with antibody titers. Serum CPV titers ${\geq}80$ were considered protective. Protective antibodies against CPV were present in 95.0% of the population. Breed, age, and primary vaccination and revaccination were not significantly associated with serum CPV antibody titers. But sex was significantly associated with CPV antibody titers. The results of this study have shown that there is a need to reconsider the annual revaccination strategy against CPV infection.

Keywords

References

  1. Appel MJG, Cooper BJ, Greisen H, Carmichael LE. Status report: Canine viral enteritis. J Am Vet Med Assoc 1978; 173: 1516
  2. Appel MJG, Cooper BJ, Greisen H, Scott F, Carmichael LE. Canine viral enteritis. 1. Status report on corona- and parvolike viral enteritis. Cornell Vet 1979; 3: 123-133
  3. Bass EP, Gill MA, Beckenhauer WH. Evaluation of a canine adenovirus type 2 strain as a replacement for infectious canine hepatitis vaccine. J Am Vet Med Assoc 1980; 177: 234-242
  4. Bohm M, Thompson A, Weir A, Hasted M, Maxwell NS, Herrtage ME. Serum antibody titers to canine parvovirus, adenovirus and distemper virus in dogs in the UK which had not been vaccinated for at least three years. Vet Rec 2004; 154: 457-463 https://doi.org/10.1136/vr.154.15.457
  5. Carmichael LE, Joubert JC, Pollock RVH. Hemagglutination by canine parvovirus: serologic studies and diagnostic applications. Am J Vet Res 1980; 41: 784-791
  6. Coyne MJ. Seroconversion of puppies to canine parvovirus and canine distemper virus: A comparison of two combination vaccine. J Am Anim Hosp Assoc 2000; 36: 137-142 https://doi.org/10.5326/15473317-36-2-137
  7. Duval D, Giger U. Vaccine-associated immune-mediated hemolytic anemia in the dog. J Vet Intern Med 1996; 10: 290-295 https://doi.org/10.1111/j.1939-1676.1996.tb02064.x
  8. Gorham JR. Duration of vaccination immunity and the influence on subsequent prophylaxis. J Am Vet Med Assoc 1966; 149: 499-704
  9. Greene CE. Immunoprophylaxis and immunotherapy. In: Infectious disease of dog and cat, 2nd ed. Philadelphia: Greene CE, WB Saunders. 1998: 723-744
  10. Harrus S, Waner T, Aizenberg I, Safra N, Mosenco A, Radoshitsky M, Bark H. Development of hypertrophic osteodystrophy and antibody response in a litter of vaccinated weimaraner puppies. J Small Anim Pract 2002; 43: 27-31 https://doi.org/10.1111/j.1748-5827.2002.tb00006.x
  11. Hirayama K, Kano R, Hosokawa-Kanai T, Tsuyama S, Nakamura Y, Sasaki Y, Hasegawa A. VP2 gene of a canine parvovirus isolate from stool of a puppy. J Med Vet Sci 2005; 67: 139-143 https://doi.org/10.1292/jvms.67.139
  12. Hogenesch H, Azxona-Ovlivera J, Scott-Moncreiff C, Snyder PW, Glickme LT. Vaccine-induced autoimmunity in the dog. Adv Vet Med 1999; 41: 733-744 https://doi.org/10.1016/S0065-3519(99)80056-1
  13. Hoskins JD. Vaccination protocol for canine parvovirus. Vet Forum 1996; 13: 60-61
  14. Kruth SA, Ellis JA. Vaccination of dogs and cats: general principles and duration of immunity. Can Vet J 1998; 39: 423-426
  15. McCaw DL, Thompson M, Tate D, Binderer A, Chen YJ. Serum distemper virus and parvovirus antibody titers among dogs brought to a veterinary hospital for revaccination. J Am Vet Med Assoc 1998; 213: 72-75
  16. Mouzin DE, Lorenzen MJ, Haworth JD, Kjng VL. Duration of serologic response to five viral antigens in dogs. J Am Vet Med Assoc 2004; 224: 55-60 https://doi.org/10.2460/javma.2004.224.55
  17. Olson P, Hedhammar A, Klingeborn B. Canine parvovirus infection, canine distemper and infectious canine hepatitis: inclination to vaccinate and antibody response in the Sweden dog population. Act Veterinaria Scandinavica 1996; 37: 433-444
  18. Olson P, Klingeborn B, Hedhammar A. Serum antibody response to canine parvovirus, canine adenovirus-1, and canine distemper virus in dogs with known status of immunization: study of dogs in Sweden. Am J Vet Res 1988; 49: 1460-1466
  19. Parrish CR, Aquadro CF, Strassheim ML, Evermann JF, Sgro JY, Mohammed HO. Rapid antigenic-type replacement and DNA sequence evolution of canine parvovirus. J Virol 1991; 65: 6544-6552
  20. Patronek GJ, Glickman LT, Johnson R, Emerick TJ. Canine distemper infection in pet dog: II. A case-control study of risk factors during a suspected outbreak in Indiana. J Am Anim Hosp Assoc 1995; 31: 230-235 https://doi.org/10.5326/15473317-31-3-230
  21. Phillips TR, Schultz RD. Canine and feline vaccines. In: Kirk RW, Bonagura JD, eds. Current veterinary therapy XI. Philadelphia: WB Saunders. 1992: 202-206
  22. Pollock RV, Carmichael LE. Maternally derived immunity to canine parvovirus infection: transfer, decline and interference with vaccination. J Am Vet Med Assoc 1982; 180: 37-42
  23. Pollock RV, Coyne MJ. Canine parvovirus. Vet Clin North Am Small Anim Pract 1993; 23: 555-568 https://doi.org/10.1016/S0195-5616(93)50305-4
  24. Smith CA. Are we vaccinating too much? J Am Vet Med Assoc 1995; 207: 421-425
  25. Schultz RD. Canine vaccines and immunity: important considerations in the success of a vaccination program, in Proceedings. Small animal immunology: new faces of immune-mediated diseases and current concept in vaccine immunology 1995; 23: 24-27
  26. Swango LJ. Canine viral disease. In: Ettinger SJ, Feldman EC, eds. Textbook of veterinary internal medicine. Philadelphia: WB Saunders. 1995: 398-409
  27. Tizard I, Ni Y. Use of serologic testing to assess immune status of companion animals. J Am Vet Med Assoc 1998; 213: 54-60
  28. Twark L, Dodds WJ. Clinical use of serum parvovirus and distemper virus antibody titers for determining revaccination strategies in healthy dogs. J Am Vet Med Assoc 2000; 217: 1021-1024 https://doi.org/10.2460/javma.2000.217.1021
  29. Wilcock BP, Yager JA. Focal cutaneous vasculitis and alopecia at site of rabies vaccination in dogs. J Am Vet Med Assoc 1986; 188: 1174-1177