Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
권호 표지

The Efficacy of Ozonated Water Therapy on Pododermatitis of Dairy Cows

젖소 족피부염(足皮膚炎)에 대한 오존수의 치료(治療) 효과(效果)

  • Lee, Soo-Jin (College of Veterinary Medicine, Chungnam National University) ;
  • Cho, Sung-Whan (College of Veterinary Medicine, Chungnam National University) ;
  • Jun, Moo-Hyung (College of Veterinary Medicine, Chungnam National University) ;
  • Kim, Duck-Hwan (College of Veterinary Medicine, Chungnam National University) ;
  • Park, Chang-Sik (Division of Animal Science & Resources, Research Center for Transgenic Cloned Pigs, Chungnam National University) ;
  • Han, Hong-Ryul (College of Veterinary Medicine, Seoul National University) ;
  • Kim, Myung-Cheol (College of Veterinary Medicine, Chungnam National University)
  • 이수진 (충남대학교 수의과대학) ;
  • 조성환 (충남대학교 수의과대학) ;
  • 전무형 (충남대학교 수의과대학) ;
  • 김덕환 (충남대학교 수의과대학) ;
  • 박창식 (충남대학교 동물자원학부, 형질전환복제돼지연구센터) ;
  • 한홍율 (서울대학교 수의과대학) ;
  • 김명철 (충남대학교 수의과대학)
  • Published : 2006.09.30
Download PDF
⟨ Previous Next ⟩

Abstract

This study was carried out to determine therapeutic the effect of ozonated water therapy on bovine pododermatitis. In addition, bactericidal effect of ozonated water on etiological agent of bovine pododermatitis was examined. The pathohistological examination for the pododermatitis, according to application with ozonated water and ozone ointment was investigated. Thirty healthy cattle were divided two groups(each of 15) : control group(povidone group), treatment group(ozone solution group). Various parameters were evaluated in terms of the lameness score, swelling score, lesion score, WBC count, neutrophil count, pathohistological finding, and antimicrobial action. The decrease of lameness and lesion score were shown in hoof lesions on 14 days after application of ozonated water. Significant decrease of swelling was shown in hoof lesions on 14 days 1Corresponding author after application of ozonated water(p<0.01). In hematological findings, WBC count revealed values within normal range. The number of neutrophils was slightly higher than that of normal, however, this was improved on 14 days after application of ozonated water. In pathohistological findings, recovery was rapid macroscopically and microscopically in the treatment with ozonated water on the hoof lesions and ozonated water was effective. In antimicobial action, bactericidal effect was observed in treatment with ozonated water on the hoof lesions and ozonated water was effective.

Keywords

References

  1. Arita M, Nagayoshi M, Fukuizumi T, Okinaga T, Masumi S, Morikawa M, Kakinoki Y, Nishihara T. Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates. Oral Microbiol Immunol 2005; 20: 206-210 https://doi.org/10.1111/j.1399-302X.2005.00213.x
  2. Beligotskii NN, Spiridonov MI, Seroshtanov AI, Trushin AS. The use of ozone for treating suppurative wounds. Klin Khir 1994; 5: 52-54
  3. Dentine MR, McDaniel BT. Variation of edema scores from herd- year, age, calving month and sire. J Dairy Sci 1983; 66: 2391-2399 https://doi.org/10.3168/jds.S0022-0302(83)82097-9
  4. Gorbunov S. Total ozone therapy of trophic ulcers of lower extremities in elderly patients. 2nd international symposium on ozone applications Havana, Cuba 1997; 24-26
  5. Greenough PR. Skin, hoof, claw and appendages. In: Textbook of large animal surgery, 2nd ed. Baltimore: Williams & Wilkins. 1988: 154-219
  6. Gundarova RA, Khoroshilova-Maslova IP, Bordiugova GG, Ilatovskaia LV, Lapina IM. Experimental validation of using ozonated physiological solution in intraocular infection. Vestn Oftalmol. 1996; 112: 9-11
  7. Hems RS, Gulabivala K, Ng Y-L, Ready D, Spratt DA. An in vitro evalluation of the ability of ozone to kill a strain of Enterococcus faecallis. International Endodontic Journal 2005; 38: 22-29 https://doi.org/10.1111/j.1365-2591.2004.00891.x
  8. Kashiwagi K, Saito K, Wang YD, Takahashi H, Ishijima K, Tsukahara S. Safety of ozonated solution as an antiseptic of the ocular surface prior to ophthalmic surgery. Ophthalmologica 2001; 215: 351-356 https://doi.org/10.1159/000050884
  9. Kotov SA. Ozone therapy of migraine. Zh Nevrol Psikhiatr Im S S Korsakova. 2000; 100: 35-37
  10. Kudriavtsev EP, Miroshin SI, Semenov SV, Snigorenko AS, Sidorovich IA. Ozone therapy of diffuse peritonitis in the early postoperative period. Khirurgiia 1997; 8: 36-41
  11. Malanchuk VA, Gorshevikova EV, Kopchak AV. Antimicrobial action of ozone in the treatment of mandibular fracture. Klin Khir 2000; 10: 43-46
  12. Malanchuk VA, Kopchak AV, Savitskaia IM, Stupina AS. Pathomorphological aspects of the inflammatory process in soft tissues during the ozone application in the experiment. Klin Khir 2000; 10: 52-55
  13. Nagayoshi M, Kitamura C, Fukuizumi T, Nishihara T, Terashita M. Antimicrobial effect of ozonated water on bacteria invading dentinal tubules. J Endod 2004; 30: 778-781 https://doi.org/10.1097/00004770-200411000-00007
  14. Ovchinnikov lu M, Sin'kov EV. Use of gaseous ozone and ozonized solutions in the treatment of chronic suppurative otitis media. Vestnik Otorinolaringologii. 1998; 6: 11-12
  15. Ozmen V, Thomas WO, Healy JT, Fish JM, Chambers R, Tacchi E, Nichols RL, Flint LM, Ferrara JJ. Irrigation of the abdominal cavity in the treatment of experimentally induced microbial peritonitis: efficacy of ozonated saline. Am Surg. 1993; 59: 297-303
  16. Perrine D, Georges P, Langlais B. The efficacy of water ozonation on the inactivation of oocysts of Cryptosporidium. Bull Acad Natl Med. 1990; 174: 845-850
  17. Rae DO, Chenoweth PJ, Brown MB, Genho PC, Moore SA, Jacobsen KE. Reproductive performance of beef heifers: Effect of vulvo-vaginitis, Ureaplasma diversum and prebreeding antibiotic administration. Theriogenology 1993; 40: 497-508 https://doi.org/10.1016/0093-691X(93)90403-R
  18. Rogenberger G. Clinical examination of cattle, Berlin and Hamburg: Verlag Paul Parley. 1979; 367-371
  19. Shakov V lu, Edeleva AN. Reasons for the application of medical ozone in the treatment of chronic purulent mesotympanitis. Vestn Otorinolaringologii. 1999; 2: 48-49
  20. Thwaiyes M, Dean S. Chronic leg ulcers. Ozone and other factors affecting healing. Aust Fam Physician 1985; 14: 292, 294, 296-298
  21. Vasil'ev IT, Markov IN, Mumladze RB, Belopol'skii AA, Vasina TA. The antibacterial and immunocorrective action of ozone therapy in peritonitis. Vestnuk Khirurgii lmeni I. I. Grekova. 1995; 154: 56-60
  22. Viebahn R. The use of ozone in medicine. Karl F. Haug Publishers, Heidelberg 1944; 7, 26-30, 38-65, 68, 90
  23. Weaver AE. Lameness. In: Bovine surgery and lameness, Oxford: Blackwell Scientific Publications. 1986: 175-223
  24. Xie W, Zhang L, Yang R. The role of ozone solution on debridement and sterilization of burn wound. Zhonghua Shao Shang Za Zhi 2000; 16: 163-165
  25. 류재홍, 송근호, 김덕환, 김명철, 신상태, 조성환. 소 발굽 질병에 대한 수침의 치료효과. 한국임상수의학회지 2002; 19: 115-120
  26. 이병우, 천성호. 오존수에 처리된 후추의 저장중 미생물 변화. 농산물저장유통학회지 1996; 3: 145-148
  27. 정순욱. 소에서 발생하는 제병의 명명, 임상검사 및 치료예방. 대한수의사회지 1994; 30: 518-535
  28. 정순욱. 소의 제병과 발굽관리에 관하여. 한국우병학회지 2000; 5: Supple. 103-123