Childhood Kidney Diseases

Korean Society of Pediatric Nephrology (대한소아신장학회)
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A Case of Acetaminophen-induced Acute Interstitial Nephritis Presenting with Acute Renal Failure

급성 신부전을 보인 아세트아미노펜에 의한 급성 간질성 신염 1례

  • Jeon, Hak-Su (Department of Pediatrics, College of Medicine, Chungbuk National University) ;
  • Ha, Tae-Sun (Department of Pediatrics, College of Medicine, Chungbuk National University)
  • 전학수 (충북대학교 의과대학 소아과학교실) ;
  • 하태선 (충북대학교 의과대학 소아과학교실)
  • Published : 2006.10.31
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Abstract

Acute interstital nephritis can occur by acetaminophen, but it is rarely presented as acute renal failure with azotemia. We report a case of acute interstitial nephritis induced by acetaminophen in a 14-year-old girl who developed non-oliguric acute renal failure. She has taken acetaminophen to control the persistent throat pain for the last two months. Renal biopsy revealed diffuse infiltration of mononuclear inflammatory cells admixed with eosinophils in the edematous interstitia. After the discontinuation of acetaminophen and the administration of corticosteroid, the serum creatinine level returned to normal.

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