Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)
- Volume 10 Issue 2
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- Pages.163-174
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- 2006
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- 1226-6531(pISSN)
NMR Studies of Zinc-binding Luteinizing Hormone Releasing Hormone
- Kim, Dae-Sung (Department of Applied Chemistry, Hanyang University) ;
- Lee, Mi-Sun (Department of Applied Chemistry, Hanyang University) ;
- Lee, Chang-Jun (Department of Applied Chemistry, Hanyang University) ;
- Won, Ho-Shik (Department of Applied Chemistry, Hanyang University)
- Published : 2006.12.20
Abstract
Luteinizing Hormone Releasing Hormone(LHRH) is a decapeptide neurotransmitter known to be regulated by metal ions in the hyperthalamus. Zn-binding LHRH complex was systhesized, and zinc-LHRH complex was studied to understand what kinds of structural modifications would be critical in the LHRH releasing mechanism. Both nonexchangeable and exchangeable