Gamma Knife Radiosurgery for Remnant or Recurred Craniopharyngiomas

  • Kwon, Young-Sub (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Park, Yong-Sook (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Chang, Jong-Hee (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Chang, Jin-Woo (Department of Neurosurgery, Yonsei University College of Medicine) ;
  • Park, Yong-Gou (Department of Neurosurgery, Yonsei University College of Medicine)
  • 발행 : 2006.02.28

초록

Objective : The authors assess the long term effectiveness of gamma knife radiosurgery[GKS] for remnant or recurred craniopharyngiomas on tumor control and possibly set proper radiation dose for tumor control with utmost preservation of the adjacent structures. Methods : Sixteen GKS were done in 14 patients with recurred or remnant craniopharyngiomas after surgery. Mean follow up duration was 44.2 months [range $11.3{\sim}123.6\;months$]. Follow up MR imagings were analyzed. Results : Mean tumor volume was $3.6cm^3$ [range $0.6{\sim}18cm^3$] and mean margin dose was 12.2Gy [range $8{\sim}22.4Gy$]. Tumor control was achieved in 87.5% [14 of 16 tumors] which were either solid or cystic in nature. Dose to optic apparatus was mean 7.9Gy and no radiation related complications were observed. Conclusion : GKS seems to be effective treatment modality for craniopharyngiomas regardless of nature of tumor whether it is cystic or solid. Dose of 8 to 8.5Gy may be sufficient to achieve long term tumor control for remnant or recurred craniopharyngiomas.

키워드

참고문헌

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