Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
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Gamma Knife Radiosurgery in Patients with a Hypothalamic Hamartoma Associated with Intractable Gelastic Epilepsy : Report of Three Cases

  • Ko, Che-Kyu (Departments of Neurosurgery, Asan Medical Center, College of Medicine, Ulsan University) ;
  • Hong, Seok-Ho (Departments of Neurosurgery, Asan Medical Center, College of Medicine, Ulsan University) ;
  • Ko, Tae-Sung (Departments of Pediatrics, Asan Medical Center, College of Medicine, Ulsan University) ;
  • Lee, Jung-Kyo (Departments of Neurosurgery, Asan Medical Center, College of Medicine, Ulsan University)
  • Published : 2006.01.30
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Abstract

Hypothalamic hamartoma[HH] is an unusual nonneoplastic developmental lesion associated with gelastic epilepsy and precocious puberty, mostly found in children. Although open surgery has been attempted when antiepileptic medication failed to control seizures, its deep location and surrounding vital structures often rendered surgery unsuccessful. We describe the outcome of gamma knife radiosurgery in three children with a HH associated with gelastic epilepsy and reviewed the literature for a possible therapeutic mechanism.

Keywords

References

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