Abstract
In order to elucidate the behavior of the insecticide imidacloprid (1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine) in crucian carp (Carassius auratus L.) and its effects on the internal organs of crucian carp, the crucian carps were exposed to [$^{14}C$]imidacloprid at a predicted environmental concentration of 0.064 mg/L for 4 days. Imidacloprid in water was absorbed into crucian carps to reach the maximum concentration at 2 days after exposure. Unknown major metabolite and imidacloprid urea, minor metabolite, were detected in test water. The amounts of the [$^{14}C$]imidacloprid and its metabolites absorbed in gall were much higher than those in the other parts, strongly suggesting that biliary excretion involving enterohepatic recirculation could be an import route for the elimination of imidacloprid absorbed in crucian carps. Meanwhile, no toxic effects of imidacloprid on liver and kidney as well as the genital organs such as testis and ovary were observed by microscopic inspection.
살충제 imidacloprid(1-(6-chloro-3-pyridylmethyl)-N-nitroimidazolidin-2-ylideneamine)의 붕어(Carassius auratus L.) 체내 행적과 장기에 미치는 영향을 구명하기 위하여 imidacloprid를 환경추정농도인 0.064 mg $kg^{-1}$로 처리한 시험수에 붕어를 4일간 경시적으로 노출시켰다. 수중의 imidacloprid는 붕어체내에 흡수되어 노출 2일차에 최대 흡수량을 나타내었으며, 다른 장기에 비해 쓸개에서 농도가 가장 높았다. 붕어 사육수에서 미확인 주대사산물과 imidacloprid urea가 대사산물로 검출되었다. 또한 붕어체내에 흡수된 imidacloprid의 주요 배설경로는 담도이었으며, 장기에 대한 조직학적 이상증상은 발견되지 않았다.
