대한의생명과학회지 (Biomedical Science Letters)
- 제12권4호
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- Pages.405-411
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- 2006
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
The Alpha Subunit of Go Interacts with Brain Specific High Mobility Group Box Containing Protein
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- 길성호 (경기대학교 생물학과)
- Park, Jung-Sik (Department of Bioiogy, Kyonggi University) ;
- Ghil, Sung-Ho (Department of Bioiogy, Kyonggi University)
- 발행 : 2006.12.31
초록
Heterotrimeric GTP binding proteins (G proteins) mediate signal transduction generated by neurotransmitter and hormones. Among G-proteins, Go is classified as a member of the Go/Gi family and the most abundant heterotrimeric G protein in brain. Most of the mechanistic analyses on the activation of Go indicated its action to be mediated by the