Biomedical Science Letters (대한의생명과학회지)
- Volume 12 Issue 4
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- Pages.385-391
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- 2006
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
The Effect of Alpha Subunit of Go on Cell Growth
- Won, Jung-Hee (Department of Biology, Kyonggi University) ;
- Ghil, Sung-Ho (Department of Biology, Kyonggi University)
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- 길성호 (경기대학교 생물학과)
- Published : 2006.12.31
Abstract
Heterotrimeric GTP binding proteins (G proteins) mediate signals generated by neurotransmitters and hormones Among G proteins, Go is found in a large quantity in brain and growth cone membranes of neurons. In spite of its abundance in neurons, the role of Go is not fully understood. In our previous study, we identified promyelocytic leukemia zinc finger protein (PLZF) as an interacting partner of alpha subunit of Go (