한국재료학회지 (Korean Journal of Materials Research)

  • 제16권5호
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  • Pages.277-284
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  • 2006
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  • 1225-0562(pISSN)
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  • 2287-7258(eISSN)
한국재료학회 (Materials Research Society of Korea)
권호 표지
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표면 개질에 따른 Ti-8wt.%Ta-3wt.%Nb 합금의 생체적합성

Biocompatibility of Ti-8wt.%Ta-3wt.%Nb alloy with Surface Modification

  • 이도재 (전남대학교 공과대학 금속공학과) ;
  • 이경구 (전남대학교 공과대학 금속공학과) ;
  • 박범수 (전남대학교 공과대학 금속공학과) ;
  • 이광민 (전남대학교 공과대학 금속공학과) ;
  • 박상원 (전남대학교 치과대학 보철학교실)
  • Lee, Doh-Jae (Dept. of Metallurgical Engineering, Chonnam National University) ;
  • Lee, Kyung-Ku (Dept. of Metallurgical Engineering, Chonnam National University) ;
  • Park, Bum-Su (Dept. of Metallurgical Engineering, Chonnam National University) ;
  • Lee, Kwang-Min (Dept. of Metallurgical Engineering, Chonnam National University) ;
  • Park, Sang-Won (Dept. of Prosthodontics, School of Dentistry, Chonnam National University)
  • 발행 : 2006.05.27
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초록

The alloys were prepared by a non-consumable vacuum arc melting and homogenized at $1050^{\circ}C$ for 24 hrs. Two kind of surface modifications were performed alkali treatment in 5.0M NaOH solution subsequent and heat treatment in vacuum furnace at $600^{\circ}C$, and were oxidizing treatment at the temperature range of 550 to $750^{\circ}C$ for 30 minutes. After surface modification, these samples were soaked in SBF which consists of nearly the same ion concentration as human blood plasma. Cytotoxicity tests were performed in MTT assay treated L929 fibroblast cell culture, using indirect methods. A porous and thin activated layer was formed on Titanium and Ti-8Ta-3Nb alloy by the alkali treatment. A bone-like hydroxyapatite was nucleated on the activated porous surfaces during the in vitro test. However, Ti-8Ta-3Nb alloys showed better bioactive properties than Titanium. According to XRD results, oxide layers composed of mostly $TiO_2$(rutile) phases. Cytotoxicity test also revealed that moderate oxidation treatment lowers cell toxicity and Ti-8Ta-3Nb alloy showed better results compared with Titanium.

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